Date published: 2025-9-8

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2-Chloroaniline (CAS 95-51-2)

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CAS Number:
95-51-2
Purity:
≥99%
Molecular Weight:
127.57
Molecular Formula:
C6H6ClN
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloroaniline is a versatile organic compound extensively utilized in both scientific research and industrial applications. As a member of the aniline family, it belongs to a group of aromatic compounds featuring a benzene ring and an amine group. 2-Chloroaniline acts as a catalyst in polymer production, particularly in the manufacturing of polyvinyl chloride (PVC). It also acts as a model compound for studying the structure and reactivity of organic molecules. With its aromatic nature encompassing a benzene ring and an amine group, 2-Chloroaniline possesses an electron-rich amine group capable of forming hydrogen bonds with other molecules. This unique characteristic renders it a potent nucleophile, facilitating reactions with a diverse array of molecules.


2-Chloroaniline (CAS 95-51-2) References

  1. Photo-induced decomposition of 2-chloroaniline in aqueous solution.  |  Winarno, EK. and Getoff, N. 2002. Z Naturforsch C J Biosci. 57: 512-5. PMID: 12132694
  2. Cement-clay pastes for stabilization/solidification of 2-chloroaniline.  |  Botta, D., et al. 2004. Waste Manag. 24: 207-16. PMID: 14761760
  3. Hydroamination/Heck reaction sequence for a highly regioselective one-pot synthesis of indoles using 2-chloroaniline.  |  Ackermann, L., et al. 2004. Chem Commun (Camb). 2824-5. PMID: 15599425
  4. Biodegradation of 2-chloroaniline, 3-chloroaniline, and 4-chloroaniline by a novel strain Delftia tsuruhatensis H1.  |  Zhang, LL., et al. 2010. J Hazard Mater. 179: 875-82. PMID: 20417029
  5. Enhanced dechlorination and biodegradation of 2-chloroaniline by a 2-aminoanthraquinone-graphene oxide composite under anaerobic conditions.  |  Lu, H., et al. 2019. Sci Rep. 9: 12376. PMID: 31451740
  6. Achiral Molecular Recognition of Substituted Aniline Position Isomers by Crown Ether Type Chiral Stationary Phase.  |  Ohnishi, A., et al. 2021. Molecules. 26: PMID: 33477703
  7. Steric Shielding Effects Induced by Intramolecular C-H⋯O Hydrogen Bonding: Remote Borylation Directed by Bpin Groups.  |  Bastidas, JRM., et al. 2022. ACS Catal. 12: 2694-2705. PMID: 36685107
  8. Highly Selective Electrocatalytic Reduction of Substituted Nitrobenzenes to Their Aniline Derivatives Using a Polyoxometalate Redox Mediator.  |  Stergiou, AD., et al. 2023. ACS Org Inorg Au. 3: 51-58. PMID: 36748077
  9. Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4.  |  Ashton, TD., et al. 2023. J Med Chem. 66: 3540-3565. PMID: 36812492
  10. Urinary bio-monitoring of aromatic amine derivatives by new needle trap device packed with the multi-component adsorbent.  |  Rahimpoor, R., et al. 2023. Sci Rep. 13: 4243. PMID: 36918633
  11. Comparison of gas chromatographic techniques for the analysis of iodinated derivatives of aromatic amines.  |  Lorenzo-Parodi, N., et al. 2023. Anal Bioanal Chem. 415: 3313-3325. PMID: 37208487
  12. Highly regioselective and diastereoselective synthesis of novel pyrazinoindolones via a base-mediated Ugi-N-alkylation sequence.  |  Tajik, M., et al. 2023. RSC Adv. 13: 16963-16969. PMID: 37288378
  13. Bladder cancer screening: The new selection and prediction model.  |  Radosavljevic, V. and Milic, N. 2023. Open Med (Wars). 18: 20230723. PMID: 37333447

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloroaniline, 1 g

sc-237990
1 g
$41.00