Date published: 2026-1-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (CAS 4090-55-5)

0.0(0)
Write a reviewAsk a question

CAS Number:
4090-55-5
Molecular Weight:
184.56
Molecular Formula:
C5H10ClO3P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (C5DMDO), a highly reactive and stable compound, can be utilized in various ways. For instance, 2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide has been used as a catalyst in the synthesis of numerous organic compounds, including 1,2-dihydro-2-oxo-1H-benzimidazole and 2-amino-4-methyl-4H-chromene. Its catalytic properties have been instrumental in facilitating these reactions. The compound acts as a Lewis acid catalyst, playing a vital role in forming covalent bonds between substrates. By acting as a proton acceptor, it enables the creation of a covalent bond between two molecules by accepting a proton from one molecule and donating it to another. 2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide acts as an electron donor, promoting the formation of covalent bonds between molecules by donating an electron to one molecule and accepting an electron from another.


2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (CAS 4090-55-5) References

  1. N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease.  |  Sidhu, R., et al. 2019. J Lipid Res. 60: 1410-1424. PMID: 31201291
  2. UPLC-MS/MS determination of steroid hormones via a novel reaction based on derivatisation by a cyclic-organophosphate.  |  Szterk, A., et al. 2019. Talanta. 204: 415-423. PMID: 31357314
  3. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy.  |  Ager, CR., et al. 2019. Bioorg Med Chem Lett. 29: 126640. PMID: 31500996
  4. E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity.  |  Kim, DS., et al. 2021. ChemMedChem. 16: 1740-1743. PMID: 33522135
  5. Reaction Mechanism Studies of Solvolytic Displacement of Chloride from Phosphorus  |  Han Joong Koh, Suk Jin Kang & Dennis N. Kevill. 2008. Phosphorus, Sulfur, and Silicon and the Related Elements. 183: 364-368.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, 25 g

sc-230164
25 g
$187.00