Date published: 2025-12-13

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2-chloro-4-phenylquinoline (CAS 5855-56-1)

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CAS Number:
5855-56-1
Molecular Weight:
239.70
Molecular Formula:
C15H10ClN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloro-4-phenylquinoline (2-CPQ) is an intriguing heterocyclic aromatic compound. In scientific research, 2-Chloro-4-phenylquinoline finds broad applications due to its remarkable ability to bind to and modulate the activity of numerous proteins and enzymes. For instance, it acts as a competitive inhibitor of cytochrome P450 2C19. Additionally, 2-Chloro-4-phenylquinoline exhibits binding capabilities to other enzymes and proteins, including cyclooxygenase-2 (COX-2) involved in prostaglandin synthesis and 5-lipoxygenase (5-LOX) involved in leukotriene synthesis.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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2-chloro-4-phenylquinoline (CAS 5855-56-1) References

  1. Novel synthesis of 2-chloroquinolines from 2-vinylanilines in nitrile solvent.  |  Lee, BS., et al. 2002. J Org Chem. 67: 7884-6. PMID: 12398521
  2. Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors.  |  Cappelli, A., et al. 2016. J Med Chem. 59: 3353-72. PMID: 26982523
  3. Beyond a Protecting Reagent: DMAP-Catalyzed Cyclization of Boc-Anhydride with 2-Alkenylanilines.  |  Huang, YN., et al. 2016. J Org Chem. 81: 4645-53. PMID: 27163704
  4. Design, synthesis, and pharmacological activities of 2-substituted 4-phenylquinolines as potential antidepressant drugs.  |  Alhaider, AA., et al. 1985. J Med Chem. 28: 1394-8. PMID: 4045918

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-chloro-4-phenylquinoline, 250 mg

sc-274529
250 mg
$175.00