Molecular structure of 2-Chloro-4-nitrophenyl α-D-maltotrioside, CAS Number: 118291-90-0
2-Chloro-4-nitrophenyl α-D-maltotrioside (CAS 118291-90-0)
Alternate Names:
CNPG3
CAS Number:
118291-90-0
Molecular Weight:
659.98
Molecular Formula:
C24H34ClNO18
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Chloro-4-nitrophenyl α-D-maltotrioside serves as a colorimetric substrate to assess α-amylase activity. The enzymatic hydrolysis of this compound generates 2-chloro-4-nitrophenol, which can be detected at 405 nm through colorimetric means. By measuring the release of 2-chloro-4-nitrophenol, the enzyme activity can be determined. This compound has been employed to study the functionality of human pancreatic or salivary amylase.
2-Chloro-4-nitrophenyl α-D-maltotrioside (CAS 118291-90-0) References
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- Total and pancreatic amylase measured with 2-chloro-4-nitrophenyl-4-O-beta-D-galactopyranosylmaltoside. | Morishita, Y., et al. 2000. Clin Chem. 46: 928-33. PMID: 10894835
- Characterization of a salt-tolerant extracellular a-amylase from Bacillus dipsosauri. | Deutch, CE. 2002. Lett Appl Microbiol. 35: 78-84. PMID: 12081555
- An ideal substrate for the measurement of pancreatic amylase? | Lorentz, K. 2002. Clin Chem Lab Med. 40: 781-5. PMID: 12392304
- Metrological traceability of values for alpha-amylase catalytic concentration assigned to a commutable calibrator materials. | Canalias, F., et al. 2010. Clin Chim Acta. 411: 7-12. PMID: 19799891
- High-resolution α-amylase assay combined with high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy for expedited identification of α-amylase inhibitors: proof of concept and α-amylase inhibitor in cinnamon. | Okutan, L., et al. 2014. J Agric Food Chem. 62: 11465-71. PMID: 25368916
- Evaluation of a combined drug-delivery system for proteins assembled with polymeric nanoparticles and porous microspheres; characterization and protein integrity studies. | Alcalá-Alcalá, S., et al. 2015. Int J Pharm. 489: 139-47. PMID: 25936624
- Progress of pancreatitis disease biomarker alpha amylase enzyme by new nano optical sensor. | Attia, MS. and Al-Radadi, NS. 2016. Biosens Bioelectron. 86: 413-419. PMID: 27419907
- Colorimetric Detection of Salivary α-Amylase Using Maltose as a Noncompetitive Inhibitor for Polysaccharide Cleavage. | Tsyrulneva, I., et al. 2019. ACS Sens. 4: 865-873. PMID: 30895774
- Genomic sequencing of Gracilibacillus dipsosauri reveals key properties of a salt-tolerant α-amylase. | Deutch, CE. and Yang, S. 2020. Antonie Van Leeuwenhoek. 113: 1049-1059. PMID: 32318981
- Antioxidant, Antibacterial, Antidiabetic Potential, and In silico Analysis of Rhus chinensis from Western Nepal. | Dhakal, K., et al. 2022. Curr Top Med Chem. 22: 2145-2151. PMID: 35927822
- Determination of total and pancreatic alpha-amylase in human serum with 2-chloro-4-nitrophenyl-alpha-D-maltotrioside as substrate. | Gella, FJ., et al. 1997. Clin Chim Acta. 259: 147-60. PMID: 9086302
- Reference values for alpha-amylase in human serum and urine using 2-chloro-4-nitrophenyl-alpha-D-maltotrioside as substrate. | Balsells, D., et al. 1998. Clin Chim Acta. 274: 213-7. PMID: 9694589
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Chloro-4-nitrophenyl α-D-maltotrioside, 1 g | sc-506551 | 1 g | $620.00 |