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2-Chloro-1,3-dimethylimidazolinium chloride (CAS 37091-73-9)

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Alternate Names:
2-Chloro-1,3-dimethyl-4,5-dihydro-3H-imidazol-1-ium chloride
Application:
2-Chloro-1,3-dimethylimidazolinium chloride is used for the synthesis of macroviracin A, cycloviracin B1, cyclic silanes, and others
CAS Number:
37091-73-9
Purity:
≥90%
Molecular Weight:
169.05
Molecular Formula:
C5H10Cl2N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloro-1,3-dimethylimidazolinium chloride is an activating agent in total synthesis of macroviracin A, cycloviracin B1, and cyclic silanes.


2-Chloro-1,3-dimethylimidazolinium chloride (CAS 37091-73-9) References

  1. Modified guanidines as potential chiral superbases. 2. Preparation Of 1,3-unsubstituted and 1-substituted 2-iminoimidazolidine derivatives and a related guanidine by the 2-chloro-1, 3-dimethylimidazolinium chloride-induced cyclization of thioureas.  |  Isobe, T., et al. 2000. J Org Chem. 65: 7774-8. PMID: 11073580
  2. Modified guanidines as potential chiral superbases. 3. Preparation Of 1,4,6-triazabicyclooctene systems and 1,4-disubstituted 2-iminoimidazolidines by the 2-chloro-1,3-dimethylimidazolinium chloride-induced cyclization of guanidines with a hydroxyethyl substituent.  |  Isobe, T., et al. 2000. J Org Chem. 65: 7779-85. PMID: 11073581
  3. Structure assignment, total synthesis, and antiviral evaluation of cycloviracin B1.  |  Fürstner, A., et al. 2003. J Am Chem Soc. 125: 13132-42. PMID: 14570487
  4. Synthetic studies on macroviracin A: a rapid construction of C(42) macrocyclic dilactone corresponding to the core.  |  Takahashi, S., et al. 2004. J Org Chem. 69: 4509-15. PMID: 15202909
  5. Direct dehydrative pyridylthio-glycosidation of unprotected sugars in aqueous media using 2-chloro-1,3-dimethylimidazolinium chloride as a condensing agent.  |  Yoshida, N., et al. 2011. Chem Asian J. 6: 1876-85. PMID: 21604376
  6. Efficient and Inexpensive Synthesis of 15N-Labeled 2-Azido-1,3-dimethylimidazolinium Salts Using Na15NO2 Instead of Na15NNN.  |  Gwak, S., et al. 2024. ACS Omega. 9: 6556-6560. PMID: 38371833
  7. Direct synthesis of 1,6-anhydro sugars from unprotected glycopyranoses by using 2-chloro-1,3-dimethylimidazolinium chloride  |  Tanaka, T., Huang, W. C., Noguchi, M., Kobayashi, A., & Shoda, S. I. 2009. Tetrahedron Letters. 50(18): 2154-2157.
  8. Protection-free synthesis of glycosyl dithiocarbamates in aqueous media by using 2-chloroimidazolinium reagent  |  Li, G., Noguchi, M., Kashiwagura, H., Tanaka, Y., Serizawa, K., & Shoda, S. I. 2016. Tetrahedron Letters. 57(31): 3529-3531.
  9. Efficient Synthesis of α‐Glycosyl Chlorides Using 2‐Chloro‐1, 3‐dimethylimidazolinium Chloride: A Convenient Protocol for Quick One‐Pot Glycosylation  |  Tatina, M. B., Khong, D. T., & Judeh, Z. M. 2018. European Journal of Organic Chemistry. 2018(19): 2208-2213.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloro-1,3-dimethylimidazolinium chloride, 5 g

sc-254191
5 g
$52.00

2-Chloro-1,3-dimethylimidazolinium chloride, 25 g

sc-254191A
25 g
$180.00