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2-C-Methyl-D-ribono-1,4-lactone (CAS 492-30-8)

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Application:
2-C-Methyl-D-ribono-1,4-lactone is used in the synthesis of a variety of compounds
CAS Number:
492-30-8
Molecular Weight:
162.14
Molecular Formula:
C6H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-C-Methyl-D-ribono-1,4-lactone, a derivative of D-ribose, has garnered interest in scientific research due to its unique chemical structure and potential applications in various fields. One of the key mechanisms of action involves its role as a precursor in the synthesis of nucleosides and nucleotides, essential components of DNA and RNA. Researchers have explored its utility as a building block for the preparation of modified nucleosides with improved properties, such as enhanced stability and bioactivity, which could find applications in nucleic acid-based diagnostics and materials science. Additionally, 2-C-Methyl-D-ribono-1,4-lactone exhibits antioxidant properties, attributed to its ability to scavenge free radicals and inhibit oxidative stress-induced damage. This antioxidative activity has sparked interest in its potential applications in food preservation, cosmetics, and nutraceuticals. Furthermore, studies have investigated its role as a chiral auxiliary in asymmetric synthesis, enabling the enantioselective preparation of complex organic molecules. Overall, the multifaceted properties of 2-C-Methyl-D-ribono-1,4-lactone make it a versatile chemical with diverse research applications spanning nucleoside chemistry, biochemistry, materials science, and organic synthesis.


2-C-Methyl-D-ribono-1,4-lactone (CAS 492-30-8) References

  1. 2-Substituted 1-azabicycloalkanes, a new class of non-opiate antinociceptive agents.  |  Carson, JR., et al. 1992. J Med Chem. 35: 2855-63. PMID: 1495016
  2. 2,3-O-(S)-Benzyl-idene-2-C-methyl-d-ribono-1,4-lactone.  |  Booth, KV., et al. 2009. Acta Crystallogr Sect E Struct Rep Online. 65: o2199. PMID: 21577602
  3. Asymmetric Synthesis of 2'-C-Methyl-4'-selenonucleosides as Anti-Hepatitis C Virus Agents.  |  Lee, H., et al. 2019. J Org Chem. 84: 14414-14426. PMID: 31608633
  4. Carbon-branched carbohydrate chirons: practical access to both enantiomers of 2-C-methyl-ribono-1,4-lactone and 2-C-methyl-arabinonolactone  |  Kathrine V. Booth a, Filipa P. da Cruz a, David J. Hotchkiss a, Sarah F. Jenkinson a, Nigel A. Jones a, Alexander C. Weymouth-Wilson b, Robert Clarkson b, Thomas Heinz c, George W.J. Fleet a. 2008. Tetrahedron: Asymmetry. 19: 2417-2424.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-C-Methyl-D-ribono-1,4-lactone, 500 mg

sc-220708
500 mg
$280.00