2-Bromopyridine-5-boronic acid (CAS 223463-14-7)
QUICK LINKS
2-Bromopyridine-5-boronic acid is a chemical compound that functions as a versatile building block in organic synthesis. It acts as a key reagent in the formation of carbon-carbon and carbon-heteroatom bonds, particularly in the Suzuki-Miyaura cross-coupling reaction. The mechanism of action involves its ability to undergo oxidative addition to a palladium catalyst, forming an arylpalladium intermediate. This intermediate then reacts with an organic electrophile, leading to the formation of a new carbon-carbon bond. 2-Bromopyridine-5-boronic acid can participate in the direct arylation of heteroarenes, enabling the construction of complex molecular structures. Its role in these reactions allows for the efficient and selective synthesis of biaryl compounds, which are useful in the development of functional materials.
2-Bromopyridine-5-boronic acid (CAS 223463-14-7) References
- An approach based on liquid chromatography/electrospray ionization-mass spectrometry to detect diol metabolites as biomarkers of exposure to styrene and 1,3-butadiene. | Shen, S., et al. 2009. Anal Biochem. 386: 186-93. PMID: 19111668
- Enhancement of the capabilities of liquid chromatography-mass spectrometry with derivatization: general principles and applications. | Xu, F., et al. 2011. Mass Spectrom Rev. 30: 1143-72. PMID: 21557289
- Non inflammatory boronate based glucose-responsive insulin delivery systems. | Dasgupta, I., et al. 2012. PLoS One. 7: e29585. PMID: 22272238
- A new derivatization approach for the rapid and sensitive analysis of brassinosteroids by using ultra high performance liquid chromatography-electrospray ionization triple quadrupole mass spectrometry. | Huo, F., et al. 2012. Talanta. 99: 420-5. PMID: 22967574
- Automated and sensitive analysis of 28-epihomobrassinolide in Arabidopsis thaliana by on-line polymer monolith microextraction coupled to liquid chromatography-mass spectrometry. | Wang, X., et al. 2013. J Chromatogr A. 1317: 121-8. PMID: 23915641
- Development of a 18F-Labeled Radiotracer with Improved Brain Kinetics for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Ischemic Brain and Glioma. | Fujinaga, M., et al. 2017. J Med Chem. 60: 4047-4061. PMID: 28422499
- Determination of Propionylbrassinolide and Its Impurities by High-Performance Liquid Chromatography with Evaporative Light Scattering Detection. | Cao, L., et al. 2018. Molecules. 23: PMID: 29495470
- A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry. | Wan, D., et al. 2022. Molecules. 27: PMID: 35011515
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Bromopyridine-5-boronic acid, 1 g | sc-259721 | 1 g | $41.00 | |||
2-Bromopyridine-5-boronic acid, 5 g | sc-259721A | 5 g | $163.00 |