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2-Bromohexanoic acid (CAS 616-05-7)

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Alternate Names:
2-Bromocaproic acid
Application:
2-Bromohexanoic acid is an internal standard
CAS Number:
616-05-7
Molecular Weight:
195.05
Molecular Formula:
C6H11BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Bromohexanoic acid, as an alkylating agent, it acts by forming covalent bonds with nucleophilic groups in proteins and nucleic acids, leading to modifications in their structure and function. 2-Bromohexanoic Acid′s mechanism of action involves the substitution of a hydrogen atom with a bromine atom, resulting in the formation of a reactive alkyl group. This alkyl group can then react with various biomolecules, altering their properties and potentially interfering with their normal biological functions. In experimental applications, 2-Bromohexanoic acid is utilized to study the effects of alkylation on specific cellular processes and to investigate the role of alkylating agents in chemical biology.


2-Bromohexanoic acid (CAS 616-05-7) References

  1. Posttranslational modification of the glycosylation inhibiting factor (GIF) gene product generates bioactive GIF.  |  Watarai, H., et al. 2000. Proc Natl Acad Sci U S A. 97: 13251-6. PMID: 11069294
  2. 6-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,2'-bipyridine as ligand for actinide(III)/lanthanide(III) separation.  |  Girnt, D., et al. 2010. Inorg Chem. 49: 9627-35. PMID: 20849125
  3. Complexation of Cm(III) with 6-(5,6-dipentyl-1,2,4-triazin-3-yl)-2,2'-bipyridine studied by time resolved laser fluorescence spectroscopy.  |  Bremer, A., et al. 2012. Dalton Trans. 41: 7582-9. PMID: 22595912
  4. Simultaneous inhibition of rhamnolipid and polyhydroxyalkanoic acid synthesis and biofilm formation in Pseudomonas aeruginosa by 2-bromoalkanoic acids: effect of inhibitor alkyl-chain-length.  |  Gutierrez, M., et al. 2013. PLoS One. 8: e73986. PMID: 24023921
  5. Visualizing the chain-flipping mechanism in fatty-acid biosynthesis.  |  Beld, J., et al. 2014. Angew Chem Int Ed Engl. 53: 14456-61. PMID: 25354391
  6. Selective Extraction of Americium(III) over Europium(III) with the Pyridylpyrazole Based Tetradentate Ligands: Experimental and Theoretical Study.  |  Wang, J., et al. 2015. Inorg Chem. 54: 10648-55. PMID: 26517736
  7. Going beyond the Control of Quorum-Sensing to Combat Biofilm Infections.  |  Abraham, WR. 2016. Antibiotics (Basel). 5: PMID: 27025518
  8. Characterization of Lanthanide Complexes with Bis-1,2,3-triazole-bipyridine Ligands Involved in Actinide/Lanthanide Separation.  |  Muller, JM., et al. 2016. Inorg Chem. 55: 11454-11461. PMID: 27740770
  9. Enhanced rhamnolipid production in Burkholderia thailandensis transposon knockout strains deficient in polyhydroxyalkanoate (PHA) synthesis.  |  Funston, SJ., et al. 2017. Appl Microbiol Biotechnol. 101: 8443-8454. PMID: 29043376
  10. Highly Efficient Trivalent Americium/Europium Separation by Phenanthroline-Derived Bis(pyrazole) Ligands.  |  Liu, Y., et al. 2018. Inorg Chem. 57: 5782-5790. PMID: 29745656
  11. Inhibitors of Bacterial Swarming Behavior.  |  Rütschlin, S. and Böttcher, T. 2020. Chemistry. 26: 964-979. PMID: 31268192
  12. Determination of urinary trans,trans-muconic acid by gas chromatography-mass spectrometry.  |  Ruppert, T., et al. 1995. J Chromatogr B Biomed Appl. 666: 71-6. PMID: 7655623

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Bromohexanoic acid, 25 g

sc-230078
25 g
$32.00