(2-Bromoethoxy)-tert-butyldimethylsilane (CAS 86864-60-0)

(2-Bromoethoxy)-tert-butyldimethylsilane is a reagent for N-protection with the TBSO-ethyl group. Treatment with Jones reagent effects hydrolysis and concomitant oxidation leading to Nc-acetic acids for further synthetic elaboration. Useful reagent for the Pd-catalyzed N-hydroxyalkylation reactions. (2-Bromoethoxy)-tert-butyldimethylsilane, known as BEDMS, is a versatile organosilicon compound extensively employed in scientific research. Its colorless and volatile liquid nature, combined with solubility in most organic solvents, makes it a valuable reagent across various applications. Primarily used in organic synthesis, BEDMS exhibits its efficacy in creating ethers, esters, and other organic compounds. Moreover, it serves as an effective catalyst, facilitating reactions, including the formation of carbon-carbon bonds. Beyond its role in organic synthesis, BEDMS finds additional applications as a surfactant, stabilizing agent, and solvent for various reactions. Acting as a nucleophilic reagent, this compound readily reacts with electrophilic molecules, enabling the formation of diverse organic compounds. Its versatility and catalytic capabilities have made (2-Bromoethoxy)-tert-butyldimethylsilane a valuable asset in the realm of scientific exploration.