Date published: 2026-4-29

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2-Bromo-4-methoxybenzoic acid (CAS 74317-85-4)

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Alternate Names:
2-Bromo-p-anisic acid; 3-Bromo-4-carboxyanisole
CAS Number:
74317-85-4
Molecular Weight:
231.04
Molecular Formula:
C8H7BrO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Bromo-4-methoxybenzoic acid is an aromatic acid that features bromine substitution, and its utility extends across the spectrum of scientific research. Within this domain, it serves as a valuable foundation for the synthesis of diverse compounds, playing a pivotal role in drug and compound development endeavors. A distinctive facet of its functionality lies in its perceived role as a proton donor, facilitating the donation of protons to the target molecule. This protonation event engenders the creation of a bromonium ion, a intermediate that subsequently participates in a range of reactions contingent upon the specific reactants and prevailing conditions.


2-Bromo-4-methoxybenzoic acid (CAS 74317-85-4) References

  1. Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring.  |  Tarzia, G., et al. 2006. ChemMedChem. 1: 130-9. PMID: 16892344
  2. First general, direct, and regioselective synthesis of substituted methoxybenzoic acids by ortho metalation.  |  Nguyen, TH., et al. 2007. J Org Chem. 72: 3419-29. PMID: 17391047
  3. Regio- and stereoselective synthesis of 2-deoxy-C-aryl glycosides via palladium catalyzed decarboxylative reactions.  |  Xiang, S., et al. 2011. Org Lett. 13: 4608-11. PMID: 21815638
  4. Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis.  |  Joshi-Pangu, A., et al. 2016. J Org Chem. 81: 7244-9. PMID: 27454776
  5. Novel Regioselective Synthesis of Urolithin Glucuronides─Human Gut Microbiota Cometabolites of Ellagitannins and Ellagic Acid.  |  Villalgordo, JM., et al. 2022. J Agric Food Chem. 70: 5819-5828. PMID: 35533350
  6. Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.  |  Battisti, UM., et al. 2023. Nutrients. 15: PMID: 36771285
  7. Recent advances in the synthesis and applications of macrocyclic arenes.  |  Han, XN., et al. 2023. Chem Soc Rev. 52: 3265-3298. PMID: 37083011

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Bromo-4-methoxybenzoic acid, 1 g

sc-483117
1 g
$150.00