Date published: 2026-4-1

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2-Bromo-1-indanone (CAS 1775-27-5)

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CAS Number:
1775-27-5
Molecular Weight:
211.06
Molecular Formula:
C9H7BrO
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Discovered in the early 2000s, 2-Bromo-1-indanone is a compound that has piqued researchers′ interest for its applications in organic synthesis and biochemistry. In the realm of organic synthesis, it has found utility as a reagent and a precursor for various heterocyclic compounds, as well as an intermediate for synthesizing indanone derivatives. In the field of biochemistry, scientists have utilized 2-Bromo-1-indanone as a substrate for studying several enzymes, including cytochrome P450.


2-Bromo-1-indanone (CAS 1775-27-5) References

  1. Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.  |  Peglion, JL., et al. 2002. J Med Chem. 45: 165-76. PMID: 11754589
  2. New thiazole derivatives as potent and selective 5-hydroxytriptamine 3 (5-HT3) receptor agonists for the treatment of constipation.  |  Imanishi, N., et al. 2003. Bioorg Med Chem. 11: 1493-502. PMID: 12628674
  3. Purification and characterization of NADPH-dependent aldo-keto reductase specific for beta-keto esters from Penicillium citrinum, and production of methyl (S)-4-bromo-3-hydroxybutyrate.  |  Itoh, N., et al. 2004. Appl Microbiol Biotechnol. 66: 53-62. PMID: 15338078
  4. Synthesis of substituted acetylenic epoxides followed by indium-catalyzed rearrangement to 2,3,5-trisubstituted furans.  |  Kang, JY. and Connell, BT. 2011. J Org Chem. 76: 2379-83. PMID: 21384932
  5. High Throughput Synthesis of 2,3,6-Trisubstituted-5,6-Dihydroimidazo[2,1-b]thiazole Derivatives.  |  Li, Y., et al. 2011. Tetrahedron Lett. 52: 696-698. PMID: 21461055
  6. Thin-layer chromatography enantioseparations on chiral stationary phases: a review.  |  Del Bubba, M., et al. 2013. Anal Bioanal Chem. 405: 533-54. PMID: 23161065
  7. Enantioselective separation of twelve pairs of enantiomers on polysaccharide-based chiral stationary phases and thermodynamic analysis of separation mechanism.  |  Zhu, B., et al. 2018. Electrophoresis. 39: 2398-2405. PMID: 29947082

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Bromo-1-indanone, 5 g

sc-225178
5 g
$114.00