2-Bromo-1-(4-dimethylaminophenyl)ethanone (CAS 37904-72-6)
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2-Bromo-1-(4-dimethylaminophenyl)ethanone serves as a fatty acid derivative, finding utility in fatty acid analysis. By reacting with fatty acids, 2-bromo-1-(4-dimethylaminophenyl)ethanone forms esters, enabling the detection of both free and esterified fatty acids. Moreover, it facilitates the profiling of fatty acids in plasma or urine samples. 2-Bromo-1-(4-dimethylaminophenyl)ethanone can be utilized in a novel analytical chemistry method for the sensitive and simultaneous determination of 5-Methylcytosine (5-mC) and its oxidation products in genomic DNA. This method involves chemical derivatization with 2-Bromo-1-(4-dimethylaminophenyl)ethanone coupled with liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS), enhancing detection sensitivities and improving chromatography separation of these critical epigenetic markers.
2-Bromo-1-(4-dimethylaminophenyl)ethanone (CAS 37904-72-6) References
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- Mass Spectrometry for Investigating the Effects of Toxic Metals on Nucleic Acid Modifications. | Xiong, J., et al. 2019. Chem Res Toxicol. 32: 808-819. PMID: 30920205
- Assessment of DNA Epigenetic Modifications. | Yuan, BF. 2020. Chem Res Toxicol. 33: 695-708. PMID: 31690070
- Quantification and mapping of DNA modifications. | Dai, Y., et al. 2021. RSC Chem Biol. 2: 1096-1114. PMID: 34458826
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Bromo-1-(4-dimethylaminophenyl)ethanone, 1 g | sc-321563 | 1 g | $250.00 | |||
2-Bromo-1-(4-dimethylaminophenyl)ethanone, 5 g | sc-321563A | 5 g | $999.00 |