Molecular structure of 2-Azido-2-deoxy-D-glucose, CAS Number: 56883-39-7
2-Azido-2-deoxy-D-glucose (CAS 56883-39-7)
See product citations (2)
Application:
2-Azido-2-deoxy-D-glucose is a glucose derivative
CAS Number:
56883-39-7
Purity:
≥97%
Molecular Weight:
205.17
Molecular Formula:
C6H11N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Azido-2-deoxy-D-glucose has been used to study the substrate specificity of galactokinase. 2-Azido-2-deoxy-D-glucose is the azido analogue of D-glucosamine and may be used as a metabolic chemical reporter by direct labelling of glycans. The azide group is used to link to a fluorescent marker, enabling secondary visualisation and identification of glycoproteins. The azide moiety of 2-azido-2-deoxy-D-glucose has been used to form triazoles via a 1,3-dipolar cycloaddition reaction in the synthesis of molecules with improved solubility used to inhibit p38a MAPK for anti-inflammation.
2-Azido-2-deoxy-D-glucose (CAS 56883-39-7) References
- Appel-Lee synthesis of glycosyl inositols, substrates for inositol dehydrogenase from Bacillus subtilis. | Daniellou, R. and Palmer, DR. 2006. Carbohydr Res. 341: 2145-50. PMID: 16729989
- A short synthesis of 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-beta-D- glucopyranose and the corresponding alpha-glucosyl chloride from D-mannose. | Pavliak, V. and Kovác, P. 1991. Carbohydr Res. 210: 333-7. PMID: 1878884
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- Novel Direct Assay for Acetyl-CoA:α-Glucosaminide N-Acetyltransferase Using BODIPY-Glucosamine as a Substrate. | Choi, Y., et al. 2015. JIMD Rep. 28: 11-8. PMID: 26493749
- Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars. | Fullam, E., et al. 2016. Open Biol. 6: PMID: 27335320
- Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose. | Shen, DL., et al. 2017. ACS Chem Biol. 12: 206-213. PMID: 27935279
- The trehalose-specific transporter LpqY-SugABC is required for antimicrobial and anti-biofilm activity of trehalose analogues in Mycobacterium smegmatis. | Wolber, JM., et al. 2017. Carbohydr Res. 450: 60-66. PMID: 28917089
- A pre-targeting strategy for imaging glucose metabolism using technetium-99m labelled dibenzocyclooctyne derivative. | Ding, J., et al. 2019. Bioorg Med Chem Lett. 29: 1791-1798. PMID: 31101473
- Bio-Orthogonal Bacterial Reactor for Remission of Heavy Metal Poisoning and ROS Elimination. | Pan, P., et al. 2019. Adv Sci (Weinh). 6: 1902500. PMID: 31871876
- Technological Advancements in External Beam Radiation Therapy (EBRT): An Indispensable Tool for Cancer Treatment. | Koka, K., et al. 2022. Cancer Manag Res. 14: 1421-1429. PMID: 35431581
- One-pot construction of carbohydrate scaffolds mediated by metal catalysts. | Mukherjee, MM., et al. 2020. RSC Adv. 10: 32450-32475. PMID: 35516477
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Azido-2-deoxy-D-glucose, 250 mg | sc-256068 | 250 mg | $246.00 |