2-Aminophenyl b-D-glucuronide HCl (CAS 15959-03-2)

2-Aminophenyl β-D-glucuronide HCl is a compound that garners attention in the realm of analytical chemistry, particularly for its use as a reference standard or calibration compound in various chromatographic and spectrometric methods. Its structure, incorporating a glucuronide moiety, makes it an important standard for studies that investigate the glucuronidation process, an essential phase II metabolic route for both endogenous substances and xenobiotics. This compound is utilized to understand the activity of the enzyme beta-glucuronidase, which hydrolyzes glucuronide conjugates, releasing the aglycone and allowing researchers to study the biological roles and fate of the liberated compounds. In environmental analytical research, 2-Aminophenyl β-D-glucuronide HCl is used as a tracer or internal standard to monitor the presence and behavior of similar compounds in wastewater treatment systems or in environmental waters. Its hydrochloride salt form aids in its solubility and stability, making it suitable for use in aqueous solutions employed in laboratory experiments.