Date published: 2026-4-2

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2-Aminophenol (CAS 95-55-6)

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Alternate Names:
2-Hydroxyaniline
CAS Number:
95-55-6
Purity:
≥98%
Molecular Weight:
109.13
Molecular Formula:
C6H7NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Aminophenol is a chemical compound that functions as a reagent in various organic synthesis reactions. It acts as a precursor in the production of dyes, and other organic compounds. In the experimental, 2-Aminophenol participates in nucleophilic aromatic substitution reactions, where it undergoes substitution with electrophiles to form new carbon-carbon or carbon-heteroatom bonds. 2-Aminophenol′s mechanism of action involves its ability to donate a lone pair of electrons from the amino group, facilitating the formation of new chemical bonds. 2-Aminophenol can undergo oxidation to form quinone derivatives, which are important intermediates in the synthesis of various organic compounds. Its reactivity and ability to undergo diverse chemical transformations make it a versatile building block in organic synthesis and development.


2-Aminophenol (CAS 95-55-6) References

  1. Genetic and biochemical comparison of 2-aminophenol 1,6-dioxygenase of Pseudomonas pseudoalcaligenes JS45 to meta-cleavage dioxygenases: divergent evolution of 2-aminophenol meta-cleavage pathway.  |  Davis, JK., et al. 1999. Arch Microbiol. 172: 330-9. PMID: 10550475
  2. A novel 2-aminophenol 1,6-dioxygenase involved in the degradation of p-chloronitrobenzene by Comamonas strain CNB-1: purification, properties, genetic cloning and expression in Escherichia coli.  |  Wu, JF., et al. 2005. Arch Microbiol. 183: 1-8. PMID: 15580337
  3. Genomic and functional analyses of the 2-aminophenol catabolic pathway and partial conversion of its substrate into picolinic acid in Burkholderia xenovorans LB400.  |  Chirino, B., et al. 2013. PLoS One. 8: e75746. PMID: 24124510
  4. Oxygenative aromatic ring cleavage of 2-aminophenol with dioxygen catalyzed by a nonheme iron complex: catalytic functional model of 2-aminophenol dioxygenases.  |  Chatterjee, S. and Paine, TK. 2015. Inorg Chem. 54: 1720-7. PMID: 25646806
  5. Mechanistic studies of the tyrosinase-catalyzed oxidative cyclocondensation of 2-aminophenol to 2-aminophenoxazin-3-one.  |  Washington, C., et al. 2015. Arch Biochem Biophys. 577-578: 24-34. PMID: 25982123
  6. Highly sensitive and simultaneous electrochemical determination of 2-aminophenol and 4-aminophenol based on poly(l-arginine)-β-cyclodextrin/carbon nanotubes@graphene nanoribbons modified electrode.  |  Yi, Y., et al. 2016. Biosens Bioelectron. 77: 353-8. PMID: 26433068
  7. Oxidation of 2-aminophenol to 2-amino-3H-phenoxazin-3-one with monochloramine in aqueous environment: A new method for APO synthesis?  |  Abou Mehrez, O., et al. 2016. Chemosphere. 145: 464-9. PMID: 26694797
  8. Dioxygen Reactivity of an Iron Complex of 2-Aminophenol-Appended Ligand: Crystallographic Evidence of the Aromatic Ring Cleavage Product of the 2-Aminophenol Unit.  |  Paul, GC., et al. 2017. Inorg Chem. 56: 729-736. PMID: 28005345
  9. One-Pot Synthesis of 3-Difluoromethyl Benzoxazole-2-thiones.  |  Li, Z., et al. 2018. Org Lett. 20: 6407-6410. PMID: 30303015
  10. Tailoring the heterojunction of TiO2 with multivalence CeO2 nanocrystals - for detection of toxic 2-aminophenol.  |  Manoj, D., et al. 2022. Food Chem Toxicol. 165: 113182. PMID: 35643232
  11. 2-aminophenol 1,6-dioxygenase: a novel aromatic ring cleavage enzyme purified from Pseudomonas pseudoalcaligenes JS45.  |  Lendenmann, U. and Spain, JC. 1996. J Bacteriol. 178: 6227-32. PMID: 8892823
  12. Novel genes encoding 2-aminophenol 1,6-dioxygenase from Pseudomonas species AP-3 growing on 2-aminophenol and catalytic properties of the purified enzyme.  |  Takenaka, S., et al. 1997. J Biol Chem. 272: 14727-32. PMID: 9169437
  13. Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway.  |  Takenaka, S., et al. 1998. Arch Microbiol. 170: 132-7. PMID: 9683650

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Aminophenol, 5 g

sc-237913
5 g
$29.00