Date published: 2026-5-17

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2-aminobutanoic acid (CAS 2835-81-6)

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Alternate Names:
H-DL-Abu-OH
CAS Number:
2835-81-6
Molecular Weight:
103.12
Molecular Formula:
C4H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Aminobutanoic acid, a naturally occurring amino acid, plays a role in the synthesis of various compounds like peptides, amino acids, and nucleic acids. Furthermore, it is instrumental in the creation of fluorescent probes utilized in imaging studies. Notably, 2-Aminobutanoic acid acts as an agonist at the GABAA receptor, a chloride ion channel that responds to ligands. Upon binding, it triggers the influx of chloride ions into the cell, inducing hyperpolarization of the cell membrane. Consequently, neuronal firing is inhibited, exerting a significant impact on cellular activity.


2-aminobutanoic acid (CAS 2835-81-6) References

  1. Development and evaluation of a boronate inhibitor of gamma-glutamyl transpeptidase.  |  London, RE. and Gabel, SA. 2001. Arch Biochem Biophys. 385: 250-8. PMID: 11368005
  2. Preparation of optically active 2-aminobutanoic acid via optical resolution by replacing crystallization.  |  Yajima, T., et al. 2007. Biosci Biotechnol Biochem. 71: 1338-41. PMID: 17485843
  3. Palladium-catalyzed direct functionalization of 2-aminobutanoic acid derivatives: application of a convenient and versatile auxiliary.  |  Fan, M. and Ma, D. 2013. Angew Chem Int Ed Engl. 52: 12152-5. PMID: 24115453
  4. Differentiation between Ripening Stages of Iberian Dry-Cured Ham According to the Free Amino Acids Content.  |  Rueda, ÁA., et al. 2020. Foods. 9: PMID: 31940912
  5. Food Authentication: Techniques, Trends and Emerging Approaches.  |  González-Domínguez, R. 2020. Foods. 9: PMID: 32191996
  6. Identification of potential metabolite markers for colon cancer and rectal cancer using serum metabolomics.  |  Wu, J., et al. 2020. J Clin Lab Anal. 34: e23333. PMID: 32281150
  7. OH radical-induced crosslinks of methionine peptides.  |  Gajewski, E., et al. 1984. Int J Radiat Biol Relat Stud Phys Chem Med. 46: 47-55. PMID: 6611320
  8. Substrate structure and amino acid/K+ symport in brush-border membrane vesicles from larval Manduca sexta midgut.  |  Parthasarathy, R., et al. 1994. J Exp Biol. 197: 237-50. PMID: 7852904

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-aminobutanoic acid, 1 g

sc-341408
1 g
$59.00

2-aminobutanoic acid, 5 g

sc-341408A
5 g
$268.00