2-Amino Adenosine CAS: 2096-10-8
MF: C10H14N6O4
MW: 282.26
An inhibitor or a substrate of adenosine kinase.

2-Amino Adenosine (CAS 2096-10-8)

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Application: An inhibitor or a substrate of adenosine kinase
CAS Number: 2096-10-8
Purity: 97%
Molecular Weight: 282.26
Molecular Formula: C10H14N6O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Amino Adenosine is a nucleoside analog as an inhibitor or a substrate of adenosine kinase from M. tuberculosis. 2-Amino Adenosine is an inhibitor of ADK (adenosine kinase).


References

Barrow, E., et al.: J. Antimicrob. Chemother., 252, 801 (2003), Long, M., et al.: J. Bacteriol., 185, 6548 (2003), Yadav, V., et al.: J. Med. Chem., 47, 1987 (2004),

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water, methanol, and DMSO.
Storage :
Store at room temperature
Melting Point :
252° C (lit.)
Boiling Point :
~798.5° C at 760 mmHg (Predicted)
Density :
~2.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.99 (Predicted)
Optical Activity :
α20/D -40°±4°, c = 1 in 0.1mol/l HCl
IC50 :
Trichomonas vaginalis: IC50 = 29.5 µM; PGK: IC50 = 3.5 mM (human)
Ki Data :
Bacillus anthracis: Ki= 68 µM
pK Values :
pKa: 13.1 (Predicted), pKb: 4.88 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
72200
MDL Number :
MFCD00053556
SMILES :
NC1=NC2=C(N=CN2[[email protected]@H]2O[[email protected]](CO)[[email protected]](O)C2O)C(N)=N1

Download SDS (MSDS)

Certificate of Analysis

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