Molecular structure of 2-Amino-8-hydroxyquinoline, CAS Number: 70125-16-5
2-Amino-8-hydroxyquinoline (CAS 70125-16-5)
Alternate Names:
2-Aminoquinolin-8-ol
CAS Number:
70125-16-5
Purity:
≥98%
Molecular Weight:
160.17
Molecular Formula:
C9H8N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Amino-8-hydroxyquinoline, appearing as a pale-yellow powder, exhibits solubility in water, ethanol, and acetone. 2-Amino-8-hydroxyquinoline has shown promising biological activities, such as antioxidant, and antimicrobial properties. Its antioxidant property is attributed to its its ability to scavenge free radicals and inhibit lipid peroxidation. It has been found to be effective against various strains of bacteria and fungi, showcasing its antimicrobial activity. 2-Amino-8-hydroxyquinoline is versatile and can be applied in diverse research areas including chemistry, biology, and biochemistry.
2-Amino-8-hydroxyquinoline (CAS 70125-16-5) References
- Investigating the activity spectrum for ring-substituted 8-hydroxyquinolines. | Musiol, R., et al. 2010. Molecules. 15: 288-304. PMID: 20110891
- Identifying chelators for metalloprotein inhibitors using a fragment-based approach. | Jacobsen, JA., et al. 2011. J Med Chem. 54: 591-602. PMID: 21189019
- Screening a fragment cocktail library using ultrafiltration. | Shibata, S., et al. 2011. Anal Bioanal Chem. 401: 1585-91. PMID: 21750879
- In silico design of small molecule inhibitors of CDK9/cyclin T1 interaction. | Randjelovic, J., et al. 2014. J Mol Graph Model. 50: 100-12. PMID: 24769691
- Effects of 2-amino-8-hydroxyquinoline interaction on the conformation of physiological isomers of human serum albumin. | Shiriskar, SM., et al. 2015. Eur Biophys J. 44: 193-205. PMID: 25761396
- Overview of CDK9 as a target in cancer research. | Morales, F. and Giordano, A. 2016. Cell Cycle. 15: 519-27. PMID: 26766294
- Newly Designed Quinolinol Inhibitors Mitigate the Effects of Botulinum Neurotoxin A in Enzymatic, Cell-Based, and ex Vivo Assays. | Bremer, PT., et al. 2017. J Med Chem. 60: 338-348. PMID: 27966961
- Antileishmanial activity of synthetic analogs of the naturally occurring quinolone alkaloid N-methyl-8-methoxyflindersin. | Torres Suarez, E., et al. 2020. PLoS One. 15: e0243392. PMID: 33370295
- Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases. | Klein, M. 2023. Pharmaceuticals (Basel). 16: PMID: 37111276
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Amino-8-hydroxyquinoline, 1 g | sc-206396 | 1 g | $123.00 |