2-Amino-6-mercaptopurine-9-D-riboside (CAS 345909-25-3)
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2-Amino-6-mercaptopurine-9-D-riboside is a nucleoside analog that is used extensively in biochemical research to study nucleic acid synthesis and metabolism. As a structural analog of the natural nucleotides found within DNA and RNA, this compound is instrumental in investigations of the mechanisms of nucleotide incorporation and the fidelity of nucleic acid polymerases. Researchers utilize this analog to probe the effects of sulfur-containing purine analogs on nucleic acid stability and structure, which is critical for understanding the dynamics of genetic material under varying biological conditions. In enzymology studies, 2-Amino-6-mercaptopurine-9-D-riboside helps elucidate the substrate specificity and mechanism of action of enzymes involved in nucleotide metabolism, providing insights into how cells regulate the synthesis and repair of their genetic code.
2-Amino-6-mercaptopurine-9-D-riboside (CAS 345909-25-3) References
- LC-MS/MS Method for Measurement of Thiopurine Nucleotides (TN) in Erythrocytes and Association of TN Concentrations With TPMT Enzyme Activity. | Bajaj, AO., et al. 2022. Front Pharmacol. 13: 836812. PMID: 35387339
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Amino-6-mercaptopurine-9-D-riboside, 1 g | sc-220700 | 1 g | $345.00 |