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2-Amino-6-mercaptopurine-13C2,15N is a compound that functions as a purine analog in experimental applications. It acts by interfering with nucleic acid synthesis and inhibiting the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). 2-Amino-6-Mercaptopurine-13c2,15n is incorporated into the DNA and RNA of cells, leading to disruption of normal cellular processes. By inhibiting HGPRT, it prevents the recycling of purine bases, ultimately leading to the depletion of intracellular purine pools. This disruption of nucleic acid synthesis and purine metabolism can result in cytotoxic effects on cells, which may be useful for studying cellular processes. The isotopic labeling of 2-Amino-6-mercaptopurine-13C2,15N allows for tracking and tracing of its metabolic fate within biological systems, providing a deeper understanding into its mechanism of action at the molecular level.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Amino-6-mercaptopurine-13C2,15N, 1 mg | sc-213744 | 1 mg | $343.00 |