Molecular structure of 2-Amino-4-methylpyridine, CAS Number: 695-34-1
2-Amino-4-methylpyridine (CAS 695-34-1)
Application:
2-Amino-4-methylpyridine is a potent inhibitor of NOS2 (iNOS)
CAS Number:
695-34-1
Molecular Weight:
108.14
Molecular Formula:
C6H8N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Amino-4-methylpyridine is a compound employed in various research fields, including organic synthesis and materials science. It serves as a building block in the synthesis of more complex molecules, such as pharmaceuticals and agrochemicals. Within organic chemistry, it is used to introduce the pyridine moiety into new compounds, leveraging its amino group for further functionalization. In materials science, 2-Amino-4-methylpyridine is investigated for its potential to create novel polymers and coordination compounds with unique properties. Additionally, its role in catalysis is examined, as the pyridine ring can act as a ligand, influencing the activity and selectivity of metal catalysts in chemical reactions.
2-Amino-4-methylpyridine (CAS 695-34-1) References
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- Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase. | Zhou, D., et al. 2009. J Med Chem. 52: 2443-53. PMID: 19323559
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- Feasibility and dosimetry studies for 18F-NOS as a potential PET radiopharmaceutical for inducible nitric oxide synthase in humans. | Herrero, P., et al. 2012. J Nucl Med. 53: 994-1001. PMID: 22582045
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- Spectrophotometric study on the proton transfer reaction between 2-amino-4-methylpyridine with 2,6-dichloro-4-nitrophenol in methanol, acetonitrile and the binary mixture 50% methanol+50% acetonitrile. | Al-Ahmary, KM., et al. 2016. Spectrochim Acta A Mol Biomol Spectrosc. 154: 135-144. PMID: 26520474
- A Diverse and Versatile Regiospecific Synthesis of Tetrasubstituted Alkylsulfanylimidazoles as p38α Mitogen-Activated Protein Kinase Inhibitors. | Ansideri, F., et al. 2018. Molecules. 23: PMID: 29361698
- Paddlewheel-type diruthenium(iii,iii) tetrakis(2-aminopyridinate) complexes with NIR absorption features: combined experimental and theoretical study. | Kataoka, Y., et al. 2019. Dalton Trans. 48: 12421-12429. PMID: 31265027
- Influence of 2-Amino-4-methylpyridine and 2-Aminopyrimidine Ligands on the Malonic Acid-Cu(II) System: Insights through Supramolecular Interactions and Photoresponse Properties. | Mandal, T., et al. 2020. ACS Omega. 5: 460-470. PMID: 31956792
- A novel Cu(II)-based DNA-intercalating agent: Structural and biological insights using biophysical and in silico techniques. | Movahedi, E., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 293: 122438. PMID: 36758364
- On the mechanism of action of 2-amino-4-methylpyridine, a morphine-like analgesic. | Bergmann, F. and Elam, R. 1980. Arch Int Pharmacodyn Ther. 247: 275-82. PMID: 6449914
- 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. | Faraci, WS., et al. 1996. Br J Pharmacol. 119: 1101-8. PMID: 8937711
- Analgesic activity of 2-amino-4-methylpyridine, a novel NO synthase inhibitor. | Pettipher, ER., et al. 1997. Inflamm Res. 46 Suppl 2: S135-6. PMID: 9297548
- Effects of intravenous nitric oxide inhibitors on endotoxin-induced fever in prepubertal pigs. | Parrott, RF., et al. 1998. Gen Pharmacol. 31: 371-6. PMID: 9703204
Inhibitor of:
NOS2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Amino-4-methylpyridine, 1 g | sc-202879 | 1 g | $32.00 |