Date published: 2026-4-4

1-800-457-3801

SCBT Portrait Logo
Seach Input

2-Acetylthiophene (CAS 88-15-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Methyl-2-thienyl ketone
CAS Number:
88-15-3
Purity:
≥98%
Molecular Weight:
126.18
Molecular Formula:
C6H6OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Acetylthiophene (2-AT) stands as a heterocyclic compound, forming a five-membered ring and comprising two carbon atoms, two sulfur atoms, and an oxygen atom. Its significance lies in its role as a pivotal intermediate during the synthesis of a range of compounds, including dyes and fragrances. The versatility of 2-Acetylthiophene has prompted extensive examination of its potential applications within the realms of medicine and biochemistry. The exact mechanism by which 2-Acetylthiophene operates remains partially veiled. Nonetheless, it is posited that the compound binds to specific receptors within the body, thereby instigating a sequence of biochemical and physiological reactions. These orchestrated responses are likely accountable for the diverse impacts attributed to 2-Acetylthiophene.


2-Acetylthiophene (CAS 88-15-3) References

  1. Solvent effects on infrared spectra of 2-acetylthiophene in organic solvents.  |  Liu, Q., et al. 2003. Spectrochim Acta A Mol Biomol Spectrosc. 59: 471-5. PMID: 12524117
  2. Infrared study on solvent-solute interactions of 2-acetylthiophene in binary mixtures.  |  Liu, Q., et al. 2004. Spectrochim Acta A Mol Biomol Spectrosc. 60: 397-400. PMID: 14670504
  3. Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry.  |  Yan, Z., et al. 2005. Rapid Commun Mass Spectrom. 19: 3322-30. PMID: 16235238
  4. Synthesis, characterization, electro chemistry, catalytic and biological activities of ruthenium(III) complexes with bidentate N, O/S donor ligands.  |  Balasubramanian, KP., et al. 2006. Spectrochim Acta A Mol Biomol Spectrosc. 65: 678-83. PMID: 16546440
  5. Generation of a structurally diverse library through alkylation and ring closure reactions using 3-dimethylamino-1-(thiophen-2-yl)propan-1-one hydrochloride.  |  Roman, G. 2013. Acta Chim Slov. 60: 70-80. PMID: 23841334
  6. Apoptotic effect of chalcone derivatives of 2-acetylthiophene in human breast cancer cells.  |  Fogaça, TB., et al. 2017. Pharmacol Rep. 69: 156-161. PMID: 27923159
  7. DFT study of the interactions between thiophene-based corrosion inhibitors and an Fe4 cluster.  |  Dao, DQ., et al. 2017. J Mol Model. 23: 260. PMID: 28801757
  8. Synthesis and evaluation of novel substituted 1,2,3-triazolyldihydroquinolines as promising antitubercular agents.  |  Marvadi, SK., et al. 2019. Bioorg Med Chem Lett. 29: 529-533. PMID: 30638877
  9. Domino Synthetic Strategy for Tetrahydrothiopyran Derivatives from Benzaldehydes, 2-Acetylfuran/2-Acetylthiophene, and Sodium Sulfide.  |  Chen, D., et al. 2020. J Org Chem. 85: 9088-9095. PMID: 32530280
  10. Condensed-phase relative Gibbs free energy and E/Z descriptors for 2-acetylthiophene and 2-acetylthiophene-N1-phenyl thiosemicarbazones.  |  Sales, ALR., et al. 2021. J Mol Model. 27: 101. PMID: 33660108
  11. Determination of the semiexperimental equilibrium structure of 2-acetylthiophene in the presence of methyl internal rotation and substituent effects compared to thiophene.  |  Dindić, C., et al. 2022. Phys Chem Chem Phys. 24: 3804-3815. PMID: 35084004
  12. RIFM fragrance ingredient safety assessment, 2-acetylthiophene, CAS registry number 88-15-3.  |  Api, AM., et al. 2023. Food Chem Toxicol. 176 Suppl 1: 113704. PMID: 36889427
  13. Cinchona-Alkaloid-Derived NN Ligands and Achiral Phosphines for Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatic and α-Chloroheteroaryl Ketones.  |  Tian, J., et al. 2023. J Org Chem. 88: 9213-9224. PMID: 37226800

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Acetylthiophene, 25 g

sc-237897
25 g
$37.00