Date published: 2026-2-12

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2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone 1,3,4,6-tetraacetate (CAS 132152-77-3)

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Application:
CAS Number:
132152-77-3
Molecular Weight:
402.35
Molecular Formula:
C16H22N2O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone 1,3,4,6-tetraacetate, a modified carbohydrate derivative, has emerged as a pivotal tool in glycobiology research, offering unique insights into glycan structure-function relationships. Its mechanism of action primarily revolves around its ability to serve as a versatile building block for the synthesis of tailored glycoconjugates with precise structural features. Researchers have exploited its chemical properties to engineer glycan-based probes and substrates for elucidating glycosylation dynamics within living systems, facilitating the study of glycan-mediated molecular recognition events and signaling pathways. Moreover, this compound has found applications in developing glycan microarrays and biosensors, enabling high-throughput screening of glycan-binding proteins and deciphering complex carbohydrate-protein interactions. In cellular studies, it has been instrumental in investigating the role of glycans in cellular processes such as adhesion, migration, and differentiation, shedding light on their implications in developmental biology and disease pathogenesis. Furthermore, its utility extends to the synthesis of glycan-modified materials for biomaterial engineering and drug delivery applications, offering promising avenues for the development of next-generation biomedical technologies. Through its diverse applications, this compound continues to advance our understanding of glycobiology and pave the way for innovative research strategies aimed at unraveling the complex roles of glycans in health and disease.


2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone 1,3,4,6-tetraacetate (CAS 132152-77-3) References

  1. N-acetylglucosaminono-1,5-lactone oxime and the corresponding (phenylcarbamoyl)oxime. Novel and potent inhibitors of beta-N-acetylglucosaminidase.  |  Horsch, M., et al. 1991. Eur J Biochem. 197: 815-8. PMID: 2029909
  2. Inhibition of beta-N-acetylglucosaminidase by glycon-related analogues of the substrate.  |  Horsch, M., et al. 1993. J Enzyme Inhib. 7: 47-55. PMID: 7510794
  3. Stereochemical requirements of chitin synthase for ligand binding at the allosteric site for N-acetylglucosamine.  |  Horsch, M., et al. 1996. Eur J Biochem. 237: 476-82. PMID: 8647088

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone 1,3,4,6-tetraacetate, 25 mg

sc-220683
25 mg
$380.00