Date published: 2026-1-17

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2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose (CAS 33639-80-4)

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Alternate Names:
2-cetamido-2-deoxy-6-O-(6-deoxy-α-L-galactopyranosyl)-D-glucopyranose; Fuc1-α-6GlcNAc
Application:
CAS Number:
33639-80-4
Molecular Weight:
367.35
Molecular Formula:
C14H25NO10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose is a compound that plays a crucial role in the biosynthesis of glycoproteins and glycolipids. Specifically, it serves as a substrate for glycosyltransferase enzymes involved in the attachment of fucose residues to glycan chains. This chemical is particularly important in the context of cellular communication and recognition processes mediated by cell surface glycoconjugates. Research on 2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose focuses on elucidating the enzymatic pathways responsible for fucosylation and its role in various biological phenomena, including immune response modulation, cell adhesion, and signaling. Studies have identified specific glycosyltransferases and regulatory factors involved in the addition of fucose residues to glycan structures, highlighting the importance of 2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose as a substrate in these enzymatic reactions. Moreover, this compound serves as a valuable tool in glycobiology research for investigating the structure-function relationships of glycan molecules and their impact on cellular processes. By understanding the mechanisms governing fucosylation and glycan biosynthesis, researchers aim to uncover novel targets for intervention in diseases associated with aberrant glycosylation patterns, such as cancer, inflammation, and autoimmune disorders. Additionally, 2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose is utilized in chemical synthesis strategies to produce structurally defined glycan probes for studying glycan-protein interactions and developing glycoengineering approaches for biotechnological and biomedical applications.


2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose (CAS 33639-80-4) References

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  2. Pseudomonas aeruginosa lectin LecB is located in the outer membrane and is involved in biofilm formation.  |  Tielker, D., et al. 2005. Microbiology (Reading). 151: 1313-1323. PMID: 15870442
  3. X-ray structures and thermodynamics of the interaction of PA-IIL from Pseudomonas aeruginosa with disaccharide derivatives.  |  Marotte, K., et al. 2007. ChemMedChem. 2: 1328-38. PMID: 17623286
  4. Adaptation of Syntenic Xyloglucan Utilization Loci of Human Gut Bacteroidetes to Polysaccharide Side Chain Diversity.  |  Déjean, G., et al. 2019. Appl Environ Microbiol. 85: PMID: 31420336
  5. Structural insights of two novel N-acetyl-glucosaminidase enzymes through in silico methods.  |  ŞahutoĞlu, AS., et al. 2020. Turk J Chem. 44: 1703-1712. PMID: 33488263

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose, 2.5 mg

sc-220679
2.5 mg
$263.00