Date published: 2025-12-13

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2,7-Diaminofluorene (CAS 525-64-4)

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Alternate Names:
2,7-Fluorenediamine
CAS Number:
525-64-4
Purity:
97%
Molecular Weight:
196.25
Molecular Formula:
C13H12N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,7-Diaminofluorene is used as substitute for the carcinogenic benzidine in the chromogenic assay of peroxidases. 2,7-Diaminofluorene is a compound that exhibits solubility in water, alcohols, and ethers, enabling its use as a reagent in the synthesis of diverse organic compounds. Moreover, it serves as useful for investigating the mechanisms of various biochemical and physiological processes.


2,7-Diaminofluorene (CAS 525-64-4) References

  1. A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene.  |  Gebran, SJ., et al. 1992. J Immunol Methods. 151: 255-60. PMID: 1629614
  2. Circular dichroism study of the interaction between mutagens and bilirubin bound to different binding sites of serum albumins.  |  Orlov, S., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 126: 68-75. PMID: 24589992
  3. Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents.  |  Stoica, S., et al. 2016. Bioorg Med Chem Lett. 26: 1145-50. PMID: 26832215
  4. Fluorescent characterization of amyloid deposits in the kidneys of mdx mice.  |  Gusel'nikova, V., et al. 2018. Eur J Histochem. 62: 2870. PMID: 29943948
  5. Structure-activity relationship (SAR) studies on the mutagenic properties of 2,7-diaminofluorene and 2,7-diaminocarbazole derivatives.  |  Kim, BW., et al. 2021. Bioorg Med Chem Lett. 31: 127662. PMID: 33227415
  6. Insights Into the Mechanisms of Brain Endothelial Erythrophagocytosis.  |  Sun, J., et al. 2021. Front Cell Dev Biol. 9: 672009. PMID: 34409026
  7. A Novel Method for Amyloid Detection in Human Tissue Load Using a Fluorescent Dye - Congo Red Analogue.  |  Guselnikova, VV., et al. 2020. Sovrem Tekhnologii Med. 12: 65-70. PMID: 34513039
  8. Preclinical safety evaluation of Macleaya Cordata extract: A re-assessment of general toxicity and genotoxicity properties in rodents.  |  Dong, Z., et al. 2022. Front Pharmacol. 13: 980918. PMID: 36034805
  9. Effect of copper ions on the associations of Azospirillum bacteria with wheat seedlings (Triticum aestivum L.).  |  Muratova, AY., et al. 2022. Vavilovskii Zhurnal Genet Selektsii. 26: 477-485. PMID: 36128570
  10. Non-clinical safety evaluation of salvianolic acid A: acute, 4-week intravenous toxicities and genotoxicity evaluations.  |  Yang, MY., et al. 2022. BMC Pharmacol Toxicol. 23: 83. PMID: 36289546
  11. Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors.  |  Hosaka, K., et al. 2023. Cancer Commun (Lond). 43: 637-660. PMID: 37120719
  12. Carcinogenicity of 2,7-diaminofluorene.  |  . 1968. Br Med J. 2: 481. PMID: 4171927

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,7-Diaminofluorene, 1 g

sc-251882
1 g
$74.00