Date published: 2026-4-30

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2,6-Dimethylbenzyl chloride (CAS 5402-60-8)

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CAS Number:
5402-60-8
Molecular Weight:
154.64
Molecular Formula:
C9H11Cl
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,6-Dimethylbenzyl chloride (2,6-DMBCl) is employed in enzymatic assays and helps prepare samples for spectroscopic studies. It is also useful in extracting proteins and other biological molecules during physiological investigations. The primary chemical activity of 2,6-Dimethylbenzyl Chloride involves electrophilic aromatic substitution reactions where its chlorine atom replaces a hydrogen atom on an aromatic ring, a process typically accelerated by catalysts like copper(II) chloride.


2,6-Dimethylbenzyl chloride (CAS 5402-60-8) References

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  2. Imidazoline-modified benzylimidazolines as h5-HT(1D/1B) serotonergic ligands.  |  Prisinzano, T., et al. 2001. Bioorg Med Chem. 9: 613-9. PMID: 11310595
  3. Heterocyclic compounds as inflammation inhibitors.  |  Sondhi, SM., et al. 2002. Curr Med Chem. 9: 1045-74. PMID: 12733983
  4. Vibronic spectroscopy of benzyl-type radicals: observation of mesityl radical in the gas phase.  |  Lee, GW. and Lee, SK. 2007. J Phys Chem A. 111: 6003-7. PMID: 17583323
  5. 5-Substituted 1H-pyrrolo[3,2-b]pyridines as inhibitors of gastric acid secretion.  |  Palmer, AM., et al. 2008. Bioorg Med Chem. 16: 1511-30. PMID: 17962023
  6. Encapsulated guest-host dynamics: guest rotational barriers and tumbling as a probe of host interior cavity space.  |  Mugridge, JS., et al. 2010. J Am Chem Soc. 132: 16256-64. PMID: 20977233
  7. Electrophilic C-H Borylation and Related Reactions of B-H Boron Cations.  |  Prokofjevs, A., et al. 2013. Organometallics. 32: PMID: 24347788
  8. Vibronic Spectrum of the Jet-Cooled 2,6-Dimethylbenzyl Radical in a Corona Excitation.  |  Lee, SK., et al. 2003. J Phys Chem A. 107: 6554-7. PMID: 26312991
  9. Synthesis of regioisomeric dimethylbenzyl mercapturic acids anticipated from the metabolism of 1,2,3-trimethylbenzene  |  Yuji Tsujimoto ∗. April 1999,. Chemosphere. Volume 38, Issue 9,: Pages 2065-2070.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,6-Dimethylbenzyl chloride, 5 g

sc-281313
5 g
$57.00