Date published: 2025-11-30

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2,6-Dihydroxy-4-methylnicotinonitrile (CAS 5444-02-0)

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Alternate Names:
3-Cyano-2,6-dihydroxy-4-methylpyridine; 2,6-Dihydroxy-3-cyano-4-methylpyridine; 3-Cyano-6-hydroxy-4-methyl-2-pyridone
CAS Number:
5444-02-0
Molecular Weight:
150.13
Molecular Formula:
C7H6N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,6-Dihydroxy-4-methylnicotinonitrile is a synthetic compound classified as a heterocyclic amine. It exhibits antimycobacterial properties against mycobacteria and is used in the synthesis of 4-hydroxycoumarin. The synthesis of 2,6-Dihydroxy-4-methylnicotinonitrile involves the reaction of 4,6-dimethylaniline with phosphorus oxychloride in an organic solvent. This compound possesses a chemical structure containing both a nucleophilic hydroxy group and a nitrogen atom. Through its reaction with sulfoxide, 2,6-Dihydroxy-4-methylnicotinonitrile generates a diazonium salt, which can be subsequently transformed into a gold electrode.


2,6-Dihydroxy-4-methylnicotinonitrile (CAS 5444-02-0) References

  1. Modifications of the Triaminoaryl Metabophore of Flupirtine and Retigabine Aimed at Avoiding Quinone Diimine Formation.  |  Wurm, KW., et al. 2022. ACS Omega. 7: 7989-8012. PMID: 35284765

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,6-Dihydroxy-4-methylnicotinonitrile, 10 g

sc-298665
10 g
$108.00

2,6-Dihydroxy-4-methylnicotinonitrile, 50 g

sc-298665A
50 g
$355.00