2,6-Difluoro-4-methoxyaniline (CAS 151414-47-0)
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2,6-Difluoro-4-methoxyaniline is a derivative of aniline and finds a broad spectrum of uses in organic synthesis and scientific research. Serving as a reagent, this colorless and water-soluble compound plays a significant role in the synthesis of diverse chemical compounds. It also finds use as a catalyst in creating polymers and as an agent to inhibit corrosion within the petroleum industry. Research has leveraged 2,6-Difluoro-4-methoxyaniline in the synthesis of varied organic compounds, polymers, and peptides, along with other biologically active compounds. Its function as a nucleophile in organic reactions is noteworthy; it forms a covalent bond with the electrophilic center of the reactant, resulting in an intermediate. This intermediate then undergoes hydrolysis to yield the desired product. The reaction′s activation is aided by a base, such as sodium hydroxide.
2,6-Difluoro-4-methoxyaniline (CAS 151414-47-0) References
- Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non-nucleoside reverse transcriptase inhibitors. | Čechová, L., et al. 2019. Antivir Chem Chemother. 27: 2040206619826265. PMID: 30788976
- Effects of fluorine bonding and nonbonding interactions on 19F chemical shifts. | Lu, Y., et al. 2022. RSC Adv. 12: 32082-32096. PMID: 36415555
- The effect of fluorine substitution on the physicochemical properties and the analgesic activity of paracetamol. | Barnard, S., et al. 1993. J Pharm Pharmacol. 45: 736-44. PMID: 7901373
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,6-Difluoro-4-methoxyaniline, 1 g | sc-266207 | 1 g | $104.00 |