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2,6-Dichloro-1,4-benzoquinone (CAS 697-91-6)

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Alternate Names:
2,6-Dichloro-2,5-cyclohexadiene-1,4-dione; 2,6-Dichloro-p-benzoquinone; 2,6-Dichlorobenzoquinone; 2,6-Dichloroquinone
CAS Number:
697-91-6
Molecular Weight:
176.98
Molecular Formula:
C6H2Cl2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,6-Dichloro-1,4-benzoquinone is an organic compound. It exhibits potent oxidizing properties and has found utility in a range of biochemical and physiological investigations, alongside its application in the synthesis of diverse organic compounds. Its reactivity, combined with low toxicity and stability, has rendered it useful in organic synthesis. Furthermore, it serves as a reagent for the synthesis of other organochlorine compounds, including polychlorinated biphenyls (PCBs).


2,6-Dichloro-1,4-benzoquinone (CAS 697-91-6) References

  1. Mass Spectrometry-Inspired Degradation of Disinfection By-Product, 2,6-Dichloro-1,4-benzoquinone, in Drinking Water by Heating.  |  Pei, J., et al. 2018. Mass Spectrom (Tokyo). 7: A0068. PMID: 29977665
  2. Hydrolysis characteristics and risk assessment of a widely detected emerging drinking water disinfection-by-product-2,6-dichloro-1,4-benzoquinone-in the water environment of Tianjin (China).  |  Li, Y., et al. 2021. Sci Total Environ. 765: 144394. PMID: 33418327
  3. Hydrolysis and Chlorination of 2,6-Dichloro-1,4-benzoquinone under conditions typical of drinking water distribution systems.  |  Mohan, A. and Reckhow, DA. 2021. Water Res. 200: 117219. PMID: 34038823
  4. Formation of trihalomethanes and haloacetic acids from 2,6-dichloro-1,4-benzoquinone during chlorination: Decomposition kinetics, conversion rates, and pathways.  |  Zhai, H., et al. 2022. Chemosphere. 291: 132729. PMID: 34718017
  5. Dummy template based molecularly imprinted solid-phase microextraction coating for analysis of trace disinfection by-product of 2,6-dichloro-1,4-benzoquinone using high-performance liquid chromatography.  |  Xue, W., et al. 2022. Talanta. 239: 123065. PMID: 34875523
  6. Immune dysfunction induced by 2,6-dichloro-1,4-benzoquinone, an emerging water disinfection byproduct, due to the defects of host-microbiome interactions.  |  Wang, J., et al. 2022. Chemosphere. 294: 133777. PMID: 35093416
  7. Degradation of 2,6-dichloro-1,4-benzoquinone by UV/H2O2/O3 treatment: Effectiveness, water matrix effects, and degradation mechanism.  |  Pan, Z., et al. 2022. Chemosphere. 296: 134014. PMID: 35182531
  8. 2,6-Dichloro-1,4-benzoquinone formation from chlorination of substituted aromatic antioxidants and its control by pre-ozonation in drinking water treatment plant.  |  Qiao, R., et al. 2022. Chemosphere. 299: 134498. PMID: 35390416
  9. Untargeted metabolomics of human keratinocytes reveals the impact of exposure to 2,6-dichloro-1,4-benzoquinone and 2,6-dichloro-3-hydroxy-1,4-benzoquinone as emerging disinfection by-products.  |  Meintani, DG., et al. 2022. Metabolomics. 18: 89. PMID: 36342571
  10. The convergence of 2,6-dichloro-1,4-benzoquinone in the whole process of lignin phenol precursor chlorination.  |  Li, Y., et al. 2023. Chemosphere. 312: 137290. PMID: 36403808
  11. Aspartame-Sweetened Tap Water: Transformation Products and 2,6-Dichloro-1,4-Benzoquinone Formation.  |  Wawryk, NJP., et al. 2023. Environ Sci Technol. 57: 1332-41. PMID: 36628463
  12. Investigation of the nephrotoxicity of 2,6-dichloro-1,4-benzoquinone disinfection by-product in mice through a 28-day toxicity test.  |  Liu, T., et al. 2023. Toxicology. 487: 153459. PMID: 36787874
  13. Action of 2,6-Dichloro-1,4-benzoquinone on the O2-Evolving Activity of Photosystem II in Chlamydomonas reinhardtii Cells with and without Cell Wall: Inhibitory Effect of Its Oxidized Form.  |  Terentyev, VV., et al. 2023. Cells. 12: PMID: 36980248

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,6-Dichloro-1,4-benzoquinone, 5 g

sc-231160
5 g
$122.00