Date published: 2026-5-1

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2,6-Diaminopurine 2′-deoxyriboside (CAS 4546-70-7)

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CAS Number:
4546-70-7
Molecular Weight:
266.26
Molecular Formula:
C10H14N6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,6-Diaminopurine 2′-deoxyriboside is a nucleoside present in the nucleic acid of all living organisms. It plays a vital role in numerous biological processes and is indispensable for life itself. This purine nucleoside is closely linked to adenosine, which serves as the fundamental building block of DNA and RNA. It serves as useful in the investigation of nucleic acid structure and function, as well as in the exploration of enzyme-catalyzed reactions. Moreover, 2,6-Diaminopurine 2′-deoxyriboside finds application in studying the mechanisms of drug action because it serves as a substrate for various enzymes involved in drug metabolism. Additionally, it contributes to the study of gene regulation by playing a role in the regulation of transcription and translation processes.


2,6-Diaminopurine 2′-deoxyriboside (CAS 4546-70-7) References

  1. Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides.  |  Kohgo, S., et al. 2004. Nucleosides Nucleotides Nucleic Acids. 23: 671-90. PMID: 15200030
  2. Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application.  |  Ge, C., et al. 2009. Appl Biochem Biotechnol. 159: 168-77. PMID: 19099210
  3. Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.  |  Arico, JW., et al. 2010. J Org Chem. 75: 1360-5. PMID: 20146451
  4. Enzymatic synthesis of nucleoside analogues using immobilized 2'-deoxyribosyltransferase from Lactobacillus reuteri.  |  Fernández-Lucas, J., et al. 2011. Appl Microbiol Biotechnol. 91: 317-27. PMID: 21476139
  5. Biotransformation of 2,6-diaminopurine nucleosides by immobilized Geobacillus stearothermophilus.  |  De Benedetti, EC., et al. 2012. Biotechnol Prog. 28: 1251-6. PMID: 22837142
  6. Metabolic activation of 2,6-diaminopurine and 2,6-diaminopurine-2'-deoxyriboside to antitumor agents.  |  Weckbecker, G. and Cory, JG. 1989. Adv Enzyme Regul. 28: 125-44. PMID: 2624171

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,6-Diaminopurine 2′-deoxyriboside, 1 g

sc-216285
1 g
$64.00