Molecular structure of 2,6-Diaminopimelic acid, CAS Number: 583-93-7
2,6-Diaminopimelic acid (CAS 583-93-7)
Alternate Names:
2,6-Diaminoheptanedioic acid
Application:
2,6-Diaminopimelic acid is 2,6-Diaminopimelic acid is a constituent of proteoglycans. sc-256355 is a mixture of LL-, DD- and meso-isomers.
CAS Number:
583-93-7
Purity:
≥95%
Molecular Weight:
190.20
Molecular Formula:
C7H14N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2,6-Diaminopimelic acid is a key compound in the field of microbiology and biochemistry, particularly in research pertaining to bacterial cell wall synthesis. It is a distinctive amino acid that is a component of the peptidoglycan layer of Gram-negative and certain Gram-positive bacteria, making it vital for the structural integrity of bacterial cell walls. Studies involving 2,6-Diaminopimelic acid often focus on the biosynthetic pathways that lead to its incorporation into peptidoglycan, which is for understanding bacterial growth and division. Additionally, the compound is utilized in enzyme characterization, where it serves as a substrate for enzymes involved in the biosynthesis and modification of peptidoglycan. In the development of antibacterial strategies, 2,6-Diaminopimelic acid is significant as it can be a target for antibiotics that disrupt cell wall synthesis.
2,6-Diaminopimelic acid (CAS 583-93-7) References
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- Effects of salinomycin and vitamin B(6) on the in vitro synthesis of lysine from the stereoisomers of 2,6-diaminopimelic acid by mixed rumen protozoa, bacteria, and their mixture. | El-Waziry, AM. 1997. J Gen Appl Microbiol. 43: 109-114. PMID: 12501342
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- Uridine nucleotides containing 2, 6-diaminopimelic acid from Escherichia coli. | COMB, DG., et al. 1961. Biochim Biophys Acta. 46: 394-7. PMID: 13694891
- [Determination of 2,6-diaminopimelic acid in swine feces and chymus]. | Völker, T., et al. 1991. Arch Tierernahr. 41: 615-21. PMID: 1953341
- Use of Fecal Indices as a Non-Invasive Tool for Ruminal Activity Evaluation in Extensive Grazing Sheep. | Orellana, C., et al. 2022. Animals (Basel). 12: PMID: 35454221
- Enzymic assays for isomers of 2,6-diaminopimelic acid in walls of Bacillus cereus and Bacillus megaterium. | Day, A. and White, PJ. 1977. Biochem J. 161: 677-85. PMID: 403912
- [Protein and amino acid metabolism in the digestive tract of growing young bulls. 2. Feed protein flow into the duodenum determined with 2,6-diaminopimelic acid as a marker for crude bacterial protein]. | Gabel, M. and Poppe, S. 1985. Arch Tierernahr. 35: 639-47. PMID: 4084061
- Methods for determining 2-6-diaminopimelic acid and 2-aminoethylphosphonic acid in gut contents. | Czerkawski, JW. 1974. J Sci Food Agric. 25: 45-55. PMID: 4816667
- Microbial protein synthesis in cattle given roughage-concentrate and all-concentrate diets: the use of 2,6-diaminopimelic acid, 2-aminoethylphosphonic acid and 35S as markers. | Whitelaw, FG., et al. 1984. Br J Nutr. 52: 249-60. PMID: 6089863
- [Determination of 2-6-diaminopimelic acid in samples of bacteria isolated from the rumen of sheep using an automatic amino acid analyzer]. | Smutný, J., et al. 1984. Vet Med (Praha). 29: 101-5. PMID: 6424315
- In vitro metabolism of the stereoisomers of 2,6-diaminopimelic acid by mixed rumen protozoa and bacteria. | El-Waziry, AM. and Onodera, R. 1996. Curr Microbiol. 33: 306-11. PMID: 8875911
- Measurement of total and separate stereoisomers of diaminopimelic acid in rumen bacteria by high-performance liquid chromatography. | el-Waziry, AM., et al. 1996. J Chromatogr B Biomed Appl. 677: 53-9. PMID: 8925102
- The estimation of 2,6-diaminopimelic acid in digesta and faeces using acid ninhydrin reagent. | Mason, VC. and Bech-Andersen, S. 1976. Z Tierphysiol Tierernahr Futtermittelkd. 36: 221-9. PMID: 952096
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,6-Diaminopimelic acid, 5 g | sc-256355 | 5 g | $234.00 | |||
2,6-Diaminopimelic acid, 25 g | sc-256355A | 25 g | $995.00 |