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2,6-Di-tert-butyl-4-nitrophenol (CAS 728-40-5)

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Alternate Names:
2,6-bis(1,1-Dimethylethyl)-4-nitrophenol; 4-Nitro-2,6-bis-(1,1-dimethylethyl)phenol
Application:
2,6-Di-tert-butyl-4-nitrophenol is an uncoupler of ATP-generating oxidative phosphorylation
CAS Number:
728-40-5
Molecular Weight:
251.32
Molecular Formula:
C14H21NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,6-Di-tert-butyl-4-nitrophenol is a chemical compound of interest in the field of organic chemistry due to its antioxidant properties. Researchers study this molecule to understand the stabilization mechanisms it provides to various materials, such as polymers, by scavenging free radicals and thereby slowing the oxidation process. Its bulky tert-butyl groups provide steric hindrance, which is a subject of study in relation to the spatial configuration and how it affects the compound′s reactivity and protective capabilities. In addition to its role in inhibiting oxidative degradation, this compound is also used in mechanistic studies to better understand the nitration process of phenolic compounds. Furthermore, its distinctive UV-Vis absorption characteristics make it a useful standard in spectroscopic analysis, where it is used to calibrate instruments and develop new analytical techniques in the investigation of phenolic antioxidants.


2,6-Di-tert-butyl-4-nitrophenol (CAS 728-40-5) References

  1. Toxicity of 2,6-Di-tert-butyl-4-Nitrophenol (DBNP).  |  Alexander, WK., et al. 2001. Appl Occup Environ Hyg. 16: 487-95. PMID: 11318392
  2. Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin.  |  Inman, AO., et al. 2003. Toxicol In Vitro. 17: 289-92. PMID: 12781207
  3. Mammalian toxicity and histopathologic effects of 2, 6-dibutyl-4-nitrophenol.  |  VESSELINOVITCH, D., et al. 1961. Toxicol Appl Pharmacol. 3: 713-25. PMID: 13925649
  4. Disposition of 2,6-di-tert-butyl-4-nitrophenol (DBNP), a submarine atmosphere contaminant, in male Sprague-Dawley rats.  |  Still, KR., et al. 2005. Environ Res. 98: 363-7. PMID: 15910791
  5. Disposition and pharmacokinetics of a lubricant contaminant, 2,6-di-tert-butyl 4-nitrophenol, in grafted human skin.  |  Pershing, LK., et al. 2006. J Appl Toxicol. 26: 402-9. PMID: 16835940
  6. A note on the excretion of 2,6-di-tert-butyl-4-nitrophenol in the rat.  |  Holder, GM., et al. 1971. Food Cosmet Toxicol. 9: 531-5. PMID: 5157311

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,6-Di-tert-butyl-4-nitrophenol, 500 mg

sc-497261
500 mg
$306.00

2,6-Di-tert-butyl-4-nitrophenol, 1 g

sc-497261A
1 g
$388.00

2,6-Di-tert-butyl-4-nitrophenol, 5 g

sc-497261B
5 g
$959.00