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2,5-Diphenyloxazole (CAS 92-71-7)

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Alternate Names:
DPO; PPO
Application:
2,5-Diphenyloxazole is used for liquid scintillation spectrometry
CAS Number:
92-71-7
Molecular Weight:
221.25
Molecular Formula:
C15H11NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,5-Diphenyloxazole (2,5-DPO) is a type of heterocyclic aromatic compound classified as an oxazole. It serves as a fluorescent probe, specifically designed for identifying particular enzymes and proteins. When introduced to a sample containing the desired enzyme or protein, 2,5-Diphenyloxazole attaches itself to the targeted molecule and emits a fluorescent signal. By detecting and measuring this signal, the concentration of the specific molecule can be determined.


2,5-Diphenyloxazole (CAS 92-71-7) References

  1. [Modifying properties of 2,5-diphenyloxazole during low-dose X-ray exposure of mice].  |  Shishkina, LN., et al. 2005. Radiats Biol Radioecol. 45: 610-5. PMID: 16304778
  2. Wavelength dependant quenching of 2,5-diphenyloxazole fluorescence by nucleotides.  |  Krishnamurthy, NV., et al. 2008. J Fluoresc. 18: 29-34. PMID: 17768610
  3. Two-photon excitation of 2,5-diphenyloxazole using a low power green solid state laser.  |  Luchowski, R. 2011. Chem Phys Lett. 501: 572-574. PMID: 21399731
  4. Piracetam induces plasma membrane depolarization in rat brain synaptosomes.  |  Fedorovich, SV. 2013. Neurosci Lett. 553: 206-10. PMID: 23994056
  5. Fluorographic detection of [3H]thymidine-labeled deoxyribonucleic acid using agarose gels infused with 2,5-diphenyloxazole prior to electrophoresis.  |  Ludlow, JW., et al. 1985. Anal Biochem. 145: 212-5. PMID: 2408500
  6. Trypanocidal Activity of 2,5-Diphenyloxazoles Isolated from the Roots of Oxytropis lanata.  |  Banzragchgarav, O., et al. 2016. J Nat Prod. 79: 2933-2940. PMID: 27797518
  7. A high-speed radiation imaging system based on liquid scintillator filled capillary arrays.  |  Song, Y., et al. 2022. Rev Sci Instrum. 93: 033702. PMID: 35365019
  8. The metabolism of 2,5-diphenyloxazole (PPO) in human lymphocytes and rat liver microsomes.  |  Ahokas, JT., et al. 1987. Pharmacol Toxicol. 61: 184-90. PMID: 3684951
  9. 2,5-Diphenyloxazole as a probe for microsomal mono-oxygenation in human and rat liver.  |  Mutch, E., et al. 1985. Xenobiotica. 15: 599-603. PMID: 4049900
  10. The phototoxicity of 2,5-diphenyloxazole (POP) and 1,4-bis(5-phenyloxazol-2-yl)benzene (POPOP).  |  Kagan, J., et al. 1984. Photochem Photobiol. 40: 479-83. PMID: 6438655
  11. Fluorographic detection of radioactivity in polyacrylamide gels with 2,5-diphenyloxazole in acetic acid and its comparison with existing procedures.  |  Skinner, MK. and Griswold, MD. 1983. Biochem J. 209: 281-4. PMID: 6847617
  12. Fluorometric study of the molecular states of 2,5-diphenyloxazole in ground mixtures with gamma-cyclodextrin.  |  Yamamoto, K., et al. 1994. Pharm Res. 11: 331-6. PMID: 8165197
  13. Metabolism of 2,5-diphenyloxazole (PPO) by trout liver microsomal mixed function monooxygenase.  |  Ahokas, JT. 1976. Res Commun Chem Pathol Pharmacol. 13: 439-47. PMID: 935635

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,5-Diphenyloxazole, 100 g

sc-214016
100 g
$136.00

2,5-Diphenyloxazole, 500 g

sc-214016A
500 g
$489.00