Date published: 2026-4-28

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2,5-Dimethyl-2,4-hexadiene (CAS 764-13-6)

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Alternate Names:
1,1,4,4-Tetramethylbuta-1,3-diene; Biisobutenyl; Biisocrotyl
Application:
2,5-Dimethyl-2,4-hexadiene is a nucleophilic alkene useful for a variety of reactions
CAS Number:
764-13-6
Purity:
≥95%
Molecular Weight:
110.20
Molecular Formula:
C8H14
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,5-Dimethyl-2,4-hexadiene is a nucleophilic alkene that has been studied in the photodechlorination of 9.10-dichloroanthracene, aromatic and aliphatic thiol additions, as a singlet oxygen acceptor in various solvents, and in its asymmetric cyclopropanation with tert-butyl diazoacetate in the presence of the new copper-bisoxazoline complex. 2,5-Dimethyl-2,4-hexadiene is classified as an aliphatic hydrocarbon and holds importance as an intermediate in various industrial processes. Research has explored its potential as a reagent in organic synthesis. Furthermore, investigations have also been conducted to assess its viability as a fuel additive.


2,5-Dimethyl-2,4-hexadiene (CAS 764-13-6) References

  1. Primary and Secondary Isotope Effects in the Photooxidation of 2,5-Dimethyl-2,4-hexadiene. Elucidation of the Reaction Energy Profile.  |  Vassilikogiannakis, G., et al. 1998. J Org Chem. 63: 6390-6393. PMID: 11672275
  2. Asymmetric cyclopropanation of 2,5-dimethyl-2,4-hexadiene by copper catalysts bearing new bisoxazoline ligands.  |  Itagaki, M., et al. 2005. J Org Chem. 70: 3292-5. PMID: 15822998
  3. 2,5-Dimethyl-2,4-hexadiene induced photodechlorination of 9,10-dichloroanthracene.  |  Saltiel, J., et al. 2009. Photochem Photobiol Sci. 8: 856-67. PMID: 19492114
  4. Computational investigation of the competition between the concerted Diels-Alder reaction and formation of diradicals in reactions of acrylonitrile with nonpolar dienes.  |  James, NC., et al. 2013. J Org Chem. 78: 6582-92. PMID: 23758325
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  6. Cobalt-Catalyzed Reductive Dimethylcyclopropanation of 1,3-Dienes.  |  Werth, J. and Uyeda, C. 2018. Angew Chem Int Ed Engl. 57: 13902-13906. PMID: 30144253
  7. Dendrimer-Encapsulated Pd Nanoparticles, Immobilized in Silica Pores, as Catalysts for Selective Hydrogenation of Unsaturated Compounds.  |  Karakanov, EA., et al. 2019. ChemistryOpen. 8: 358-381. PMID: 30976477
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  10. Dearomative (3+2) Cycloadditions between Indoles and Vinyldiazo Species Enabled by a Red-Shifted Chromium Photocatalyst.  |  Gall, BK., et al. 2022. Angew Chem Int Ed Engl. 61: e202212187. PMID: 36063422
  11. Comparative analysis of Fenghuang Dancong, Tieguanyin, and Dahongpao teas using headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry and chemometric methods.  |  Li, Z. 2022. PLoS One. 17: e0276044. PMID: 36228035
  12. Molecular flavin catalysts for C-H functionalisation and derivatisation of dehydroamino acids.  |  Rehpenn, A., et al. 2022. Chem Sci. 13: 14151-14156. PMID: 36540823
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,5-Dimethyl-2,4-hexadiene, 250 ml

sc-238383
250 ml
$79.00