Molecular structure of 2,5-Diamino-4,6-dihydroxypyrimidine, CAS Number: 40769-69-5
2,5-Diamino-4,6-dihydroxypyrimidine (CAS 40769-69-5)
CAS Number:
40769-69-5
Molecular Weight:
142.12
Molecular Formula:
C4H6N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2,5-Diamino-4,6-dihydroxypyrimidine, also referred to as 2,5-diaminopyrimidine, is a chemical compound with a presence in diverse biological systems. It holds significant importance in the biosynthesis of proteins. It has exhibited potent inhibitory effects on dihydrofolate reductase, an enzyme involved in the synthesis of purines and pyrimidines. 2,5-diamino-4,6-dihydroxypyrimidine has an ability to bind to and inhibit dihydrofolate reductase. This pivotal enzyme plays a vital role in the synthesis of purines and pyrimidines, essential components for DNA and RNA production.
2,5-Diamino-4,6-dihydroxypyrimidine (CAS 40769-69-5) References
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- A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis. | Frelin, O., et al. 2015. Biochem J. 466: 137-45. PMID: 25431972
- Folate analogues. 22. Synthesis and biological evaluation of two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system. | Nair, MG., et al. 1983. J Med Chem. 26: 1164-8. PMID: 6410065
- The synthesis of functionalized derivatives of pyrimido[4,5-b][1,4]oxazines and side chain attachment | Merritt J. Winchester. 1979. 16: 1455-1458.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,5-Diamino-4,6-dihydroxypyrimidine, 100 mg | sc-266132 | 100 mg | $41.00 |