Molecular structure of 2,5-Anhydro-D-glucitol-1,6-diphosphate, CAS Number: 4429-47-4
2,5-Anhydro-D-glucitol-1,6-diphosphate (CAS 4429-47-4)
Alternate Names:
2,5-Anhydro-D-glucitol-1,6-diphosphate is known as a phosphofructokinase inhibitor.
Application:
2,5-Anhydro-D-glucitol-1,6-diphosphate is an effective competitive inhibitor of phosphofructokinase.
CAS Number:
4429-47-4
Molecular Weight:
324.12
Molecular Formula:
C6H14O11P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
2,5-Anhydro-D-glucitol-1,6-diphosphate is an effective competitive inhibitor of PFK (phosphofructokinase). 2,5-Anhydro-D-glucitol-1,6-diphosphate is a sugar phosphate compound that derives from glucose and comprises two glucose molecules connected by an anhydroglucose bridge. It finds utility as a substrate in biochemical investigations, serving as a marker for glucose metabolism and aiding the exploration of glucose metabolism regulation within cells. It has demonstrated the ability to enhance glucose uptake in cells, highlighting its potential impact on cellular glucose utilization.
2,5-Anhydro-D-glucitol-1,6-diphosphate (CAS 4429-47-4) References
- PFKP Signaling at a Glance: An Emerging Mediator of Cancer Cell Metabolism. | Lang, L., et al. 2019. Adv Exp Med Biol. 1134: 243-258. PMID: 30919341
- PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation. | Chen, J., et al. 2022. Cell Discov. 8: 52. PMID: 35641476
- On the mechanism of action of fructose 1,6-diphosphatase. Inhibition by structural analogs of fructose 1,6-diphosphate. | Benkovic, SJ., et al. 1971. Biochemistry. 10: 4881-7. PMID: 4332461
- Periodate oxidations of enamines. I. Oxidation of adenosine 5'-monophosphate in the presence of methylamine. | Rammler, DH. 1971. Biochemistry. 10: 4699-705. PMID: 4334582
- An examination of D-fructose 1,6-diphosphate and related sugar phosphates by fourier transform 31 P nuclear magnetic resonance spectroscopy. | Gray, GR. 1971. Biochemistry. 10: 4705-11. PMID: 5140187
Inhibitor of:
Enzyme, and PFK.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,5-Anhydro-D-glucitol-1,6-diphosphate, 5 mg | sc-220805 | 5 mg | $1438.00 | |||
2,5-Anhydro-D-glucitol-1,6-diphosphate, 10 mg | sc-220805A | 10 mg | $2866.00 | |||
2,5-Anhydro-D-glucitol-1,6-diphosphate, 25 mg | sc-220805B | 25 mg | $4090.00 |