Date published: 2026-6-2

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2,4′-Dihydroxydiphenyl Sulfone (CAS 5397-34-2)

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CAS Number:
5397-34-2
Molecular Weight:
250.27
Molecular Formula:
C12H10O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,4′-Dihydroxydiphenyl Sulfone is an isomeric mixture categorized within the aromatic hydrocarbons group. It binds with and triggers activation of the constitutive androstane receptor, a G protein-coupled receptor. 2,4′-Dihydroxydiphenyl Sulfone is used in thermal printing applications. Additionally, 2,4′-Dihydroxydiphenyl Sulfone contributes to the development of black leuco dyes.


2,4′-Dihydroxydiphenyl Sulfone (CAS 5397-34-2) References

  1. Synthetic polymers adsorbing bisphenol A and its analogues prepared by covalent molecular imprinting using bisphenol A dimethacrylate as a template molecule.  |  Ikegami, T., et al. 2004. Anal Bioanal Chem. 378: 1898-902. PMID: 14762648
  2. Certain Physical Properties of Some Substituted Diphenyl Sulfones and Sulfoxides.  |  Amstutz, ED., et al. 1950. Science. 111: 305-7. PMID: 17779707
  3. Predicting anti-androgenic activity of bisphenols using molecular docking and quantitative structure-activity relationships.  |  Yang, X., et al. 2016. Chemosphere. 163: 373-381. PMID: 27561732
  4. Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.  |  Kamata, R., et al. 2018. Toxicol In Vitro. 46: 335-349. PMID: 28927721
  5. A tiered high-throughput screening approach for evaluation of estrogen and androgen receptor modulation by environmentally relevant bisphenol A substitutes.  |  Keminer, O., et al. 2020. Sci Total Environ. 717: 134743. PMID: 31836225
  6. Ionic Liquid-Based Surfactants: Recent Advances in Their Syntheses, Solution Properties, and Applications.  |  El Seoud, OA., et al. 2021. Polymers (Basel). 13: PMID: 33808369
  7. In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals.  |  Matteo, G., et al. 2023. Toxicol Sci. 191: 266-275. PMID: 36534918

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4′-Dihydroxydiphenyl Sulfone, 25 g

sc-485099
25 g
$65.00

2,4′-Dihydroxydiphenyl Sulfone, 500 g

sc-485099A
500 g
$459.00