Date published: 2026-5-2

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2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (CAS 86404-63-9)

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Application:
2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone is shows antifungal activity, particularly toward Candida albicans and Candida parapsilosis
CAS Number:
86404-63-9
Molecular Weight:
223.18
Molecular Formula:
C10H7F2N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone is a specialized chemical compound featuring a core structure that combines a triazole ring and a difluorinated acetophenone group. This compound is of particular interest in synthetic chemistry and materials science due to its unique electronic properties, which arise from the electron-withdrawing effects of the fluorine atoms and the electron-donating characteristics of the triazole ring. These properties make it a valuable intermediate in the synthesis of more complex organic molecules, especially those with potential applications in the development of advanced materials or as building blocks in organic synthesis. The triazole component is well-known for its ability to act as a coordinating ligand, which can bind to various metals, thus forming coordination complexes that are crucial in catalysis and in the creation of metal-organic frameworks (MOFs). Research involving 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone often focuses on exploring these interactions and harnessing them for the synthesis of novel compounds with desired physical and chemical properties. Additionally, its use extends to the field of heterocyclic chemistry, where it contributes to the exploration of new pathways for synthesizing triazole-containing compounds, which are prominent in many areas of chemical research due to their stability and versatile chemical reactivity.


2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (CAS 86404-63-9) References

  1. Novel alkylated azoles as potent antifungals.  |  Shrestha, SK., et al. 2017. Eur J Med Chem. 133: 309-318. PMID: 28395217
  2. Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells.  |  Benhamou, RI., et al. 2017. ACS Chem Biol. 12: 1769-1777. PMID: 28472585

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone, 5 g

sc-209322
5 g
$134.00