2,4-Dichlorobenzoyl chloride (CAS 89-75-8)
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2,4-Dichlorobenzoyl chloride (2,4-DCBC) is an essential organic compound. It presents itself as a colorless to yellowish liquid, displaying solubility in most organic solvents. Esteemed for its efficacy as a reagent in organic synthesis, 2,4-Dichlorobenzoyl chloride plays a pivotal role in the preparation of diverse compounds. It serves as a valuable component in the synthesis of heterocyclic compounds, including quinolones, pyrimidines, and thiophenes. As an electrophilic reagent, 2,4-Dichlorobenzoyl chloride exhibits an inclination to react with nucleophiles such as amines, alcohols, and carboxylic acids. This reaction proceeds through nucleophilic substitution, resulting in the replacement of chlorine atoms in 2,4-Dichlorobenzoyl chloride by the nucleophilic counterparts.
2,4-Dichlorobenzoyl chloride (CAS 89-75-8) References
- Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its in silico and in vitro investigations for RNR, DNA binding, urease inhibition and radical scavenging activities. | Khalid, A., et al. 2022. RSC Adv. 12: 17194-17207. PMID: 35755589
- Influence of the ortho effect in the solvolyses of dichlorobenzoyl chlorides | Kyoung-Ho Park, Dennis N. Kevill. 2012. 25: 2-8.
- Synthesis, structure, DNA and protein binding studies, and cytotoxic activity of nickel(II) complexes containing 3,3-dialkyl/aryl-1-(2,4-dichlorobenzoyl)thiourea ligands | N. Selvakumaran a, N.S.P. Bhuvanesh b, A. Endo c, R. Karvembu a. 2014. Polyhedron. 75: 95-109.
- Preparation, characterization and in vitro antioxidant and cytotoxicity studies of some 2,4-dichloro-N-[di(alkyl/aryl)carbamothioyl] benzamide derivatives | Nanjappan Gunasekaran a, Vellingiri Vadivel b, Nathan R. Halcovitch c, Edward R.T. Tiekink d. 2017. Chemical Data Collections. 1-9: 263-276.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,4-Dichlorobenzoyl chloride, 5 g | sc-238321 | 5 g | $33.00 | |||
2,4-Dichlorobenzoyl chloride, 100 g | sc-238321A | 100 g | $64.00 |