Date published: 2025-9-5

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2,4,6-Trimethylpyridine (CAS 108-75-8)

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Alternate Names:
2,4,6-Collidine
CAS Number:
108-75-8
Molecular Weight:
121.18
Molecular Formula:
C8H11N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A tissue fixative for electron microscopy. 2,4,6-Trimethylpyridine is an aromatic heterocyclic compound and plays a role as an intermediate in the synthesis of diverse compounds. Its significance extends to being a starting material for the manufacturing of dyes and agrochemicals.


2,4,6-Trimethylpyridine (CAS 108-75-8) References

  1. Monomeric, tetrameric, and polymeric copper di-tert-butyl phosphate complexes containing pyridine ancillary ligands.  |  Murugavel, R., et al. 2004. Inorg Chem. 43: 945-53. PMID: 14753814
  2. pH of solution greatly affects sorption of ionizable compounds into low-density polyethylene film.  |  Ishikawa, H., et al. 2005. J Agric Food Chem. 53: 3488-92. PMID: 15853392
  3. Syntheses, structures and spectroscopy of uni- and bi-dentate nitrogen base complexes of silver(I) trifluoromethanesulfonate.  |  Di Nicola, C., et al. 2010. Dalton Trans. 39: 908-22. PMID: 20066236
  4. [Determination of 2-acetyl-1-pyrroline in aroma rice using gas chromatography-mass spectrometry].  |  Ying, X., et al. 2010. Se Pu. 28: 782-5. PMID: 21261047
  5. Evaluation of acid-labile S-protecting groups to prevent Cys racemization in Fmoc solid-phase peptide synthesis.  |  Hibino, H., et al. 2014. J Pept Sci. 20: 30-5. PMID: 24357151
  6. NMR study of CHN hydrogen bond and proton transfer in 1,1-dinitroethane complex with 2,4,6-trimethylpyridine.  |  Tupikina, EY., et al. 2015. J Phys Chem A. 119: 659-68. PMID: 25532047
  7. Catalytic Radical Trifluoromethylalkynylation of Unactivated Alkenes.  |  Zhou, S., et al. 2017. Org Lett. 19: 698-701. PMID: 28102684
  8. Effect of collidine (2,4,6-trimethylpyridine) on the osmiophilia and chromaffin reaction in the synaptic vesicles of rat pineal nerves.  |  Tomsig, JL. and Pellegrino de Iraldi, A. 1987. Histochemistry. 87: 21-5. PMID: 2886454
  9. Cadmium exposure disrupts the olfactory sensitivity of fire ants to semiochemicals.  |  Yang, F., et al. 2021. Environ Pollut. 287: 117359. PMID: 34020258
  10. Effect of collidine (2,4,6-trimethylpyridine) on rat pineal gland and vas deferens nerves. Further evidence for a monoamine-releasing effect.  |  Tomsig, JL. and Pellegrino de Iraldi, A. 1988. Histochemistry. 89: 301-6. PMID: 3403302
  11. Sublethal Exposure to Cadmium Induces Chemosensory Dysfunction in Fire Ants.  |  Yang, F., et al. 2022. Environ Sci Technol. 56: 12440-12451. PMID: 35944015
  12. 2,4,6-Trimethylpyridine-Derived Vinylene-Linked Covalent Organic Frameworks for Confined Catalytic Esterification.  |  Meng, F., et al. 2022. Angew Chem Int Ed Engl. 61: e202210447. PMID: 36099563
  13. Effect of pyridine and its methylated derivatives on storage by rat pineal nerves of monoaminergic neurotransmitter.  |  Pellegrino de Iraldi, A., et al. 1994. Histochemistry. 101: 419-25. PMID: 7960941

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4,6-Trimethylpyridine, 100 ml

sc-256341
100 ml
$98.00