Date published: 2026-4-25

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2,4,6-Trimethylphenyl isothiocyanate (CAS 6095-82-5)

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Alternate Names:
Mesityl isothiocyanate
CAS Number:
6095-82-5
Molecular Weight:
177.27
Molecular Formula:
C10H11NS
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,4,6-Trimethylphenyl isothiocyanate, derived from isothiocyanates, is an organosulfur compound exhibiting distinct characteristics. This colorless liquid possesses a potent, pungent odor. Notably, 2,4,6-Trimethylphenyl isothiocyanate displays enzymatic activity, facilitating the breakdown of proteins, peptides, and other macromolecules. Through the cleavage of peptide bonds between amino acids, it effectively breaks down these macromolecules into smaller fragments. Additionally, it has the ability to form covalent bonds with proteins and peptides, leading to the creation of new macromolecules. It can be used as a catalyst, and an intermediate in dye production. When combined with dimethyldioxirane, it yields diphenylphosphine acid, which, upon reacting with choline, generates sulfines. These sulfines then undergo hydrogenation to yield the desired product. Furthermore, 2,4,6-Trimethylphenyl isothiocyanate acts as a catalyst in the reaction between sulfur and hydrogen gas at high temperatures, producing hydrogen sulfide gas.


2,4,6-Trimethylphenyl isothiocyanate (CAS 6095-82-5) References

  1. Synthesis of new thiazolo[4,5-d]pyrimidines as Corticotropin releasing factor modulators.  |  Kuppast, B., et al. 2014. Med Chem. 11: 50-9. PMID: 25059547
  2. The Role of Poly-Herbal Extract in Sodium Chloride-Induced Oxidative Stress and Hyperlipidemia in Male Wistar Rats.  |  Olorunnisola, OS., et al. 2021. Medicines (Basel). 8: PMID: 34072736

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4,6-Trimethylphenyl isothiocyanate, 5 g

sc-260278
5 g
$69.00

2,4,6-Trimethylphenyl isothiocyanate, 25 g

sc-260278A
25 g
$271.00