2,4,5-Trimethoxycinnamic acid (CAS 24160-53-0)

2,4,5-Trimethoxycinnamic acid (TMCA) is a natural phenolic compound abundant in various plants, including apple and coffee. Derived from cinnamic acid, it plays a role in the essential oil of rosemary. The numerous biological activities of 2,4,5-Trimethoxycinnamic acid have garnered significant attention in recent research. As an antioxidant, it effectively scavenges free radicals, preventing oxidative damage to cells. Moreover, its antimicrobial properties have been explored, as it exhibits the ability to inhibit the growth of several pathogenic bacteria. Additionally, its anti-inflammatory effects have been demonstrated, reducing inflammation in cells. The mechanism of action behind 2,4,5-Trimethoxycinnamic acid′s antioxidant activity involves the scavenging of free radicals, which are harmful molecules causing oxidative damage to cells. Furthermore, it disrupts the production of pro-inflammatory molecules, such as cytokines and chemokines, mitigating inflammation. Its impact on bacterial growth is also evident, as it disturbs the bacterial cell membrane, hindering their growth.