2,3:5,6-Di-O-isopropylidene-L-gulonolactone (CAS 7306-64-1)

2,3:5,6-Di-O-isopropylidene-L-gulonolactone, a derivative of L-gulonolactone, plays a crucial role in various research applications, particularly in the synthesis of carbohydrate-based compounds and the study of carbohydrate chemistry. Its unique structure, featuring two isopropylidene groups attached to the hydroxyl groups at positions 2, 3, 5, and 6 of the gulonolactone ring, provides stability and protection to the reactive hydroxyl moieties, making it a versatile building block for the synthesis of complex carbohydrates and glycoconjugates. Researchers have utilized this compound as a precursor in the synthesis of various carbohydrate derivatives, such as glycosides, glycosylamines, and glycosyl esters, through selective deprotection and functional group manipulation strategies. Additionally, 2,3:5,6-Di-O-isopropylidene-L-gulonolactone has been employed in the study of carbohydrate metabolism and enzymology, serving as a substrate for enzymes involved in glycoside hydrolysis, glycosyl transfer reactions, and carbohydrate modification processes. Furthermore, its use as a protecting group in carbohydrate synthesis enables the selective manipulation of specific hydroxyl groups, facilitating the controlled construction of oligosaccharides and glycoconjugates with desired structures and properties. Overall, 2,3:5,6-Di-O-isopropylidene-L-gulonolactone remains an indispensable tool in carbohydrate research, enabling the synthesis of diverse carbohydrate-based molecules and advancing our understanding of carbohydrate biochemistry and biology.