Date published: 2025-9-5

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2,3-Hexanedione (CAS 3848-24-6)

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Alternate Names:
Acetyl butyryl
Application:
2,3-Hexanedione is used to evaluate the influence of xanthan concentration on the release of aroma compounds in xanthan-thickened food model systems
CAS Number:
3848-24-6
Purity:
≥90%
Molecular Weight:
114.14
Molecular Formula:
C6H10O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3-Hexanedione is a compound that plays a role in research across several scientific domains, particularly in organic chemistry and food science. It is frequently utilized as a reagent in the synthesis of fine chemicals and as a building block in the preparation of various organic compounds due to its dicarbonyl structure. In the realm of flavor chemistry, 2,3-Hexanedione is studied for its contribution to the flavors and aromas of certain foods and beverages, being a component found in coffee, beer, and other products. Its presence and formation are of interest in studies on food quality, shelf life, and the development of desired flavor profiles. Moreover, 2,3-Hexanedione serves as a model compound in the investigation of Maillard reactions, which are complex chemical processes responsible for the browning and flavor generation in cooked foods.


2,3-Hexanedione (CAS 3848-24-6) References

  1. Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, dibromoacetonitrile and 2-hydroxypropionitrile induce chromosome loss in Saccharomyces cerevisiae.  |  Zimmermann, FK. and Mohr, A. 1992. Mutat Res. 270: 151-66. PMID: 1383732
  2. Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH.  |  Zilz, TR., et al. 2007. Toxicology. 231: 210-4. PMID: 17229511
  3. (R)-3-hydroxyhexan-2-one is a major pheromone component of Anelaphus inflaticollis (Coleoptera: Cerambycidae).  |  Ray, AM., et al. 2009. Environ Entomol. 38: 1462-6. PMID: 19825301
  4. Identification and measurement of diacetyl substitutes in dry bakery mix production.  |  Day, G., et al. 2011. J Occup Environ Hyg. 8: 93-103. PMID: 21253982
  5. Evaluation of the hypersensitivity potential of alternative butter flavorings.  |  Anderson, SE., et al. 2013. Food Chem Toxicol. 62: 373-81. PMID: 24007741
  6. Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase.  |  Calam, E., et al. 2016. Appl Environ Microbiol. 82: 1706-1721. PMID: 26729717
  7. Chemical Reactivity and Respiratory Toxicity of the α-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione.  |  Morgan, DL., et al. 2016. Toxicol Pathol. 44: 763-83. PMID: 27025954
  8. Increased sensitivity of OSHA method analysis of diacetyl and 2,3-pentanedione in air.  |  LeBouf, R. and Simmons, M. 2017. J Occup Environ Hyg. 14: 343-348. PMID: 27792470
  9. The Male-Produced Aggregation-Sex Pheromone of the Cerambycid Beetle Plagionotus detritus ssp. detritus.  |  Molander, MA., et al. 2019. J Chem Ecol. 45: 28-36. PMID: 30413986
  10. Exposures and Emissions in Coffee Roasting Facilities and Cafés: Diacetyl, 2,3-Pentanedione, and Other Volatile Organic Compounds.  |  LeBouf, RF., et al. 2020. Front Public Health. 8: 561740. PMID: 33072698
  11. Key aroma compounds and metabolic profiling of Debaryomyces hansenii L1-1-fermented Flos Sophorae.  |  Zhang, Q., et al. 2021. J Food Biochem. 45: e13711. PMID: 33772810
  12. Effects of E-Cigarette Flavoring Chemicals on Human Macrophages and Bronchial Epithelial Cells.  |  Morris, AM., et al. 2021. Int J Environ Res Public Health. 18: PMID: 34769627
  13. Assessment of worker chemical exposures in California vape shops.  |  Attfield, KR., et al. 2022. J Occup Environ Hyg. 19: 197-209. PMID: 35156905
  14. Synthesis of α-hydroxy ketones and vicinal (R,R)-diols by Bacillus clausii DSM 8716T butanediol dehydrogenase.  |  Muschallik, L., et al. 2020. RSC Adv. 10: 12206-12216. PMID: 35497574
  15. Inhibition of the reconstituted mitochondrial oxoglutarate carrier by arginine-specific reagents.  |  Stipani, I., et al. 1996. Arch Biochem Biophys. 331: 48-54. PMID: 8660682

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3-Hexanedione, 25 g

sc-230860
25 g
$66.00