Date published: 2025-9-25

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2,3-Diphospho-D-glyceric acid pentasodium salt (CAS 102783-53-9)

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Alternate Names:
2,3-DPG; D-Glycerate 2,3-diphosphate sodium salt
Application:
2,3-Diphospho-D-glyceric acid pentasodium salt is an glycolysis metabolite which reduces oxygenation by binding to hemaglobin
CAS Number:
102783-53-9
Purity:
≥90%
Molecular Weight:
375.95
Molecular Formula:
C3H3O10P25Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3-Diphospho-D-glyceric acid pentasodium salt (2,3-DPG) is a useful intermediate in the synthesis of nucleotides and amino acids. It is also used in the laboratory as a substrate for enzyme assays, as a buffer for biochemical reactions, and as a cofactor for enzymes. Additionally, 2,3-Diphospho-D-glyceric acid pentasodium salt is involved in the regulation of oxygen transport. It is synthesized from glucose and is found in red blood cells, where it acts as a buffer for pH regulation.


2,3-Diphospho-D-glyceric acid pentasodium salt (CAS 102783-53-9) References

  1. Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition.  |  Ambele, MA. and Egan, TJ. 2012. Malar J. 11: 337. PMID: 23043460
  2. A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing.  |  Acker, JP., et al. 2014. Transfusion. 54: 2534-43. PMID: 24805193
  3. Hemoglobin Structure and Function in the Rat-Tailed Sea Cucumber, Paracaudina chilensis.  |  Baker, SM. and Terwilliger, NB. 1993. Biol Bull. 185: 115-122. PMID: 29300596
  4. Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro.  |  Morais, I., et al. 2022. Front Cell Infect Microbiol. 12: 840968. PMID: 35372095
  5. 2,3-Diphosphoglycerate and the Protective Effect of Pyruvate Kinase Deficiency against Malaria Infection-Exploring the Role of the Red Blood Cell Membrane.  |  Carvalho, M., et al. 2023. Int J Mol Sci. 24: PMID: 36674863
  6. Biochemistry of whole blood in poly(ethylene-co-ethylacrylate) experimental blood containers.  |  Horowitz, B., et al. 1985. Vox Sang. 48: 143-9. PMID: 3984300

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3-Diphospho-D-glyceric acid pentasodium salt, 25 mg

sc-213964
25 mg
$138.00

2,3-Diphospho-D-glyceric acid pentasodium salt, 100 mg

sc-213964A
100 mg
$367.00

2,3-Diphospho-D-glyceric acid pentasodium salt, 500 mg

sc-213964B
500 mg
$1234.00

What is the availability of sc-213964A (2,3-Diphospho-D-glyceric acid pentasodium salt). I.e. if I order from Sweden how long does it take to come. Is it currently available. Your competitor Sigma Aldrich only has it available in September!

Asked by: CdeB
Thank you for your question. We are happy to provide you with a shipping lead time for this chemical, however we recommend you contact our European Support Office to obtain the most accurate information. Please call our European Support office toll-free at 00800 4573 8000, email europe@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2017-07-18
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Rated 5 out of 5 by from HorowitzHorowitz, B. et al. (PubMed 3984300) investigated the biochemical status of whole blood stored in containers fabricated pf ethylene ethylacrylate (EEA) film. Whole blood in EEA developed significantly higher levels of plasma hemoglobin, erythrocyte osmotic fragility, and D-glycerate-2,3-diphosphate, and somewhat greater glucose utilization, lactate production, and pH. -SCBT Publication Review
Date published: 2015-09-15
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2,3-Diphospho-D-glyceric acid pentasodium salt | CAS 102783-53-9 is rated 5.0 out of 5 by 1.
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