Molecular structure of 2,3-dinor Prostaglandin E1, CAS Number: 7046-40-4
2,3-dinor Prostaglandin E1 (CAS 7046-40-4)
Alternate Names:
2,3-dinor PGE1
Application:
2,3-dinor Prostaglandin E1 is a metabolite of PGE1
CAS Number:
7046-40-4
Molecular Weight:
326.4
Molecular Formula:
C18H30O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Prostaglandin E1 (PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including erectile dysfunction, peripheral occlusive vascular disease,and in neonatal cardiology(1,2) The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. Inhibition of this pathway or saturation by excess substrate could, in theory, lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published.
2,3-dinor Prostaglandin E,[object Object], (CAS 7046-40-4) References
1. Virag, R., Shoukry, K., Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases. J Urol 145 287-293 (1991). 2. Hoshi, K. Approved indications of lipo-PGE1 in Japan. Advanced Drug Delivery Reviews 20 171-176 (1996).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,3-dinor Prostaglandin E1, 25 µg | sc-223465 | 25 µg | $57.00 | |||
2,3-dinor Prostaglandin E1, 50 µg | sc-223465A | 50 µg | $109.00 |