Date published: 2026-3-6

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2,3-Dimercapto-1-propanol (CAS 59-52-9)

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CAS Number:
59-52-9
Purity:
95%
Molecular Weight:
124.23
Molecular Formula:
C3H8OS2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3-Dimercapto-1-propanol is chelator is a compound with chelating properties, enabling it to form bonds with heavy metals, facilitating their removal. The substance is a focus of extensive scientific inquiry within the fields of toxicology. it serves as a tool in the body′s response to oxidative stress and free radical-induced damage. 2,3-Dimercapto-1-propanol operates by latching onto metals, creating a compound that is then expelled through urine and hinders the formation of metalloproteins, thereby blocking metals from interacting with other bodily molecules.


2,3-Dimercapto-1-propanol (CAS 59-52-9) References

  1. Amelioration by BAL (2,3-dimercapto-1-propanol) and DMPS (sodium 2,3-dimercapto-1-propanesulfonic acid) of arsenite developmental toxicity in mice.  |  Domingo, JL., et al. 1992. Ecotoxicol Environ Saf. 23: 274-81. PMID: 1376232
  2. Kinetics of reaction between molecular oxygen and 2, 3-dimercapto-1-propanol in aqueous solution.  |  RIPPIE, EG. and HIGUCHI, T. 1962. J Pharm Sci. 51: 776-9. PMID: 14492422
  3. 2,3-Dimercapto-1-propanol does not alter the porphobilinogen synthase inhibition but decreases the mercury content in liver and kidney of suckling rats exposed to HgCl2.  |  Roza, T., et al. 2005. Basic Clin Pharmacol Toxicol. 96: 302-8. PMID: 15755313
  4. Stimulation of intracellular Ca2+ elevation in neutrophils by thiol-oxidizing phenylarsine oxide.  |  Wang, JP., et al. 2005. Biochem Pharmacol. 69: 1225-34. PMID: 15794943
  5. 2,3 Dimercapto-1-propanol inhibits HIV-1 tat activity, viral production, and infectivity in vitro.  |  Kubota, S., et al. 1990. AIDS Res Hum Retroviruses. 6: 919-27. PMID: 2202353
  6. Determination of dehydroascorbic acid using high-performance liquid chromatography with coulometric electrochemical detection.  |  Dhariwal, KR., et al. 1990. Anal Biochem. 189: 18-23. PMID: 2278385
  7. Purification and properties of nucleotide pyrophosphatase from human placenta.  |  Yano, T., et al. 1985. J Biochem. 98: 1097-107. PMID: 3001038
  8. In Vitro Assessment of the Efficacy of a Macrocyclic Chelator in Reversing Methylmercury Toxicity.  |  Nobre, P., et al. 2019. Int J Environ Res Public Health. 16: PMID: 31801208
  9. Rapid Speciation of Lead in Human Blood and Urine Samples Based on MWCNTs@DMP by Dispersive Ionic Liquid-Suspension-Micro-Solid Phase Extraction.  |  Esmaeili, N., et al. 2021. Biol Trace Elem Res. 199: 2496-2507. PMID: 33034808
  10. Influence of dimercaprol (2,3-dimercapto-1-propanol) on the pharmacokinetics of 111In-bleomycin in the P-1798 lymphoma-bearing BALB/c mouse.  |  Sartiano, GP., et al. 1980. Oncology. 37: 120-4. PMID: 6153783
  11. BAL increases the arsenic-74 content of rabbit brain.  |  Hoover, TD. and Aposhian, HV. 1983. Toxicol Appl Pharmacol. 70: 160-2. PMID: 6612733
  12. Effect of canavanine and 2,3-dimercapto-1-propanol (British antilewisite) on the proliferation of Novikoff hepatoma cells in the presence of concanavalin A.  |  Doyle, DG., et al. 1983. Clin Physiol Biochem. 1: 305-17. PMID: 6680093
  13. Reversible nephrotoxic reactions to a combined 2,3-dimercapto-1-propanol and calcium disodium ethylenediaminetetraacetic acid regimen in asymptomatic children with elevated blood lead levels.  |  Moel, DI. and Kumar, K. 1982. Pediatrics. 70: 259-62. PMID: 7099793
  14. Interference by 2, 3-dimercapto-1-propanol (BAL) in angiotensin I radioimmunoassay.  |  Shapiro, R. and Page, LB. 1976. J Lab Clin Med. 88: 222-31. PMID: 956683

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3-Dimercapto-1-propanol, 5 ml

sc-256286
5 ml
$200.00

2,3-Dimercapto-1-propanol, 25 ml

sc-256286A
25 ml
$660.00