2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic Acid γ-Lactone (CAS 289697-66-1)

2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic Acid γ-Lactone, a synthetic derivative of sialic acid, has garnered significant interest in glycobiology and carbohydrate chemistry research due to its structural similarity to naturally occurring sialic acid derivatives. This compound serves as a valuable tool in investigating sialic acid biology and glycan-mediated interactions. Researchers utilize 2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic Acid γ-Lactone as a chemical probe in studies examining sialic acid recognition by lectins, antibodies, and other carbohydrate-binding proteins. Its structural modification allows for the modulation of sialic acid interactions with glycan-binding proteins, enabling detailed investigations into the molecular recognition events underlying various biological processes. Additionally, this compound has been employed in the synthesis of sialic acid analogs and glycoconjugates for studying their roles in cell adhesion, immune recognition, and pathogen-host interactions. Furthermore, 2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic Acid γ-Lactone serves as a substrate for sialyltransferases and other glycosyltransferases, facilitating the enzymatic synthesis of structurally diverse sialylated glycans. Its utility as a chemical tool and synthetic intermediate underscores its significance in advancing our understanding of sialic acid biology and its implications in various physiological and pathological processes.