2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl bromide (CAS 4348-68-9)

2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl bromide plays a crucial role in carbohydrate chemistry research, primarily as a versatile building block for the synthesis of arabinofuranosides and related carbohydrate derivatives. Its mechanism of action involves the activation of the anomeric carbon of the arabinose moiety through bromide leaving group, facilitating glycosylation reactions with various acceptor molecules. This chemical has been extensively utilized in the synthesis of arabinosides, glycoconjugates, and glycolipids, contributing to the development of diverse molecular probes and research tools. Researchers have employed these synthetic compounds to investigate biological processes involving arabinose-containing molecules, such as carbohydrate metabolism, host-pathogen interactions, and cell surface recognition events. Additionally, the structural diversity afforded by arabinofuranosides has led to their exploration in drug discovery efforts, particularly in antimicrobial, antiviral, and anticancer research. Moreover, studies focusing on the stereochemical and regioselective aspects of glycosylation reactions using 2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl bromide have provided insights into fundamental carbohydrate chemistry principles and synthetic methodologies, further advancing our understanding of carbohydrate structure-function relationships and paving the way for the development of novel carbohydrate-based diagnostic tools in various research domains.