Molecular structure of 2,3,5,6-Tetramethylpyrazine, CAS Number: 1124-11-4
2,3,5,6-Tetramethylpyrazine (CAS 1124-11-4)
Application:
2,3,5,6-Tetramethylpyrazine is used in research and treatment of multiple disorders
CAS Number:
1124-11-4
Purity:
≥98%
Molecular Weight:
136.19
Molecular Formula:
C8H12N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2,3,5,6-Tetramethylpyrazine is a naturally occurring compound derived from plants. In vitro studies have unveiled its antioxidant, antifungal, and anti-inflammatory activities. The precise mechanism of action of 2,3,5,6-Tetramethylpyrazine is not yet fully elucidated. However, it is believed to exert its effects by modulating the activity of various enzymes, receptors, and proteins involved in signal transduction pathways.
2,3,5,6-Tetramethylpyrazine (CAS 1124-11-4) References
- 2,3,5,6-Tetramethylpyrazine of Ephedra sinica regulates melanogenesis and inflammation in a UVA-induced melanoma/keratinocytes co-culture system. | Yeom, GG., et al. 2014. Int Immunopharmacol. 18: 262-9. PMID: 24333010
- Nuclear quadrupole resonance investigation of hydrogen bonding in some cocrystals of 2,3,5,6-tetramethylpyrazine and carboxylic acids. | Seliger, J. and Žagar, V. 2014. J Phys Chem B. 118: 996-1002. PMID: 24405004
- 2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells. | Gong, X., et al. 2016. Arch Toxicol. 90: 2187-2200. PMID: 26404762
- 2,3,5,6-Tetramethylpyrazine improves diet-induced whole-body insulin resistance via suppressing white adipose tissue lipolysis in mice. | Xiang, Y., et al. 2020. Biochem Biophys Res Commun. 532: 605-612. PMID: 32900485
- Increasing Yield of 2,3,5,6-Tetramethylpyrazine in Baijiu Through Saccharomyces cerevisiae Metabolic Engineering. | Cui, DY., et al. 2020. Front Microbiol. 11: 596306. PMID: 33324376
- 2,3,5,6-Tetramethylpyrazine protects retinal photoreceptors against endoplasmic reticulum stress by modulating ATF4-mediated inhibition of PRP aggregation. | Huang, H., et al. 2021. J Mol Med (Berl). 99: 383-402. PMID: 33409554
- Pyrazines Biosynthesis by Bacillus Strains Isolated from Natto Fermented Soybean. | Kłosowski, G., et al. 2021. Biomolecules. 11: PMID: 34827734
- 2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells. | Jung, YY., et al. 2022. Biomolecules. 12: PMID: 35883447
- Optimization of the production of roasted-nutty aroma by a newly isolated fungus Tolypocladium inflatum SRH81 and impact of encapsulation on its quality. | Fadel, HHM., et al. 2022. J Genet Eng Biotechnol. 20: 159. PMID: 36418666
- Aroma-active volatiles and rheological characteristics of the plastic mass during conching of dark chocolate. | Guckenbiehl, Y., et al. 2022. Food Res Int. 162: 112063. PMID: 36461389
- Production of Tetramethylpyrazine from Cane Molasses by Bacillus sp. TTMP20. | Li, Y., et al. 2023. Molecules. 28: PMID: 36985611
- Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes. | Feng, XF., et al. 2023. Front Cell Neurosci. 17: 1125412. PMID: 37051111
- Characteristics and Discrimination of the Commercial Chinese Four Famous Vinegars Based on Flavor Compositions. | Hu, Y., et al. 2023. Foods. 12: PMID: 37174404
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,3,5,6-Tetramethylpyrazine, 25 g | sc-225644 | 25 g | $46.00 |